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U
Targeting O
Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation PMID 18645041
Nodinitib
FTT5 LLNs 2803606
MK
FOXO1 promotes cancer cell growth through MDM2
BNC375 1557240
B7
FGF19 promotes cell autophagy and cisplatin chemoresistance by activating MAPK signaling in ovarian cancer PMID 36751636
Linopirdine 105431
Kaempferol
Hck promotes IL
Improved synthesis, molecular modeling and anti
Crnn Rat Pre
Cisapride 81098
SJB2
PLLA8000
MRTX849 analog 24 2490716
CCR2 signaling regulates anti
Diguanylate Cyclase, Agrobacterium vitis
PLLA4000
Mitogen
<i>Dodonaea uscosa</i>
人结直肠癌类器官培养试剂盒 Plus (Human Colorectal Cancer Organoid Plus Kit)
Transient receptor potential ankyrin 1 contributes to the ATP
MCE
New insights into quercetin's attenuation of TBBPA
L
Inhibition of protein synthesis in vitro by cycloheximide and related glutarimide antibiotics PMID 5853493
Famotidine impurity 3 (Famotidine impurity C)
KRas G12C inhibitor 2 2206735
OX40 Ligand/TNFSF4 蛋白, Rat (HEK293, His)
Methyl L
Targeting Myeloid Differentiation Using Potent 2
MicroRNA
NOTCH signaling orchestrates the inflammatory
H
Polydatin alleviates oxidative stress and pro
Covalent organic frameworks
Dual
Appenolide A 148077
18 0
Pharmacokinetics of haloperidol PMID 2689040
Ppp2r5c
Neuroligin
(7S,8S)
GLPG0492 (R enantiomer) 1215085
Engineered Biomimetic Nanovesicles Based on Neutrophils for Hierarchical Targeting Therapy of Acute Respiratory Distress Syndrome PMID 38166370
10
Samioside 360768
PDKs
癸基
PLEOF hydrogels
22
Small molecule
Hsa
HY
Role of a differentially expressed cAMP phosphodiesterase in regulating the induction of resistance against oxidative damage in Leishmania donovani PMID 19733234
Effect of luteinizing hormone releasing hormone (LHRH) and an LHRH antagonist of hypothalamic and plasma LHRH of hypophysectomized rats PMID 765115
Atrial natriuretic peptide protects vertebral endplate chondrocytes against H2O2‑induced apoptosis and oxidative stress through activation of the Nrf2/HO‑1 signaling pathway PMID 34476501
Ginsenoside Rd Inhibits Glioblastoma Cell Proliferation by Up
acidic peptide
SPP1 represents a therapeutic target that promotes the progression of oesophageal squamous cell carcinoma by driving M2 macrophage infiltration PMID 38600327
1
PEG3
MCE
Mechanotransduction, immunoregulation, and metabolic functions of CD31 in cardiovascular pathophysiology PMID 31119265
Human Serum Albumin
Desmethyl Erlotinib
1
Aza
Cyclin E in normal physiology and disease states PMID 34052101
干扰素α10（IFNA10）基因
Eperisone 64840
Maternal vitamin D regulates the metabolic rearrangement of offspring CD4+ T cells in response to intestinal inflammation PMID 40512616
两面神激酶 3（Jak3）基因
MGAT2
D44 826998
PLGA nanoparticles engineering extracellular vesicles from human umbilical cord mesenchymal stem cells ameliorates polyethylene particles induced periprosthetic osteolysis PMID 37904168
L
Non
Rosnilimab 2412764
Fenirofibrate impurity 8 (Fenirofibrate impurity F)
Application of Structure
Glyoxalase I inhibitor 3 1415388
Control of nutrient uptake by IRF4 orchestrates innate immune memory PMID 37697097
Lopinavir impurity 1 (Lopinavir impurity K)
Adjuvant
Irbesartan impurity 4 (Losartan Dibromo Impurity)
(S)
Frizzled
Montelukast impurity 15
Hydroxy ipronidazole
2
Heterogeneity and transcriptional drivers of triple
Melatonin enhances the ability of M2 macrophages to secrete IL10 by inhibiting Erk5 signaling pathway PMID 37647773
Verapamil
Polysaccharide of Lactobacillus casei SB27 reduced colon cancer cell prognosis through mitochondrial damage by upregulation of HINT2 PMID 36271660
A6CDQ 1005550
MCE
Poly(A)
Roflumilast Impurity E 1391052
Development of a Redox
MCE
Evocalcet 870964
Z
IP3RPEP6 3061802
Prolyl Endopeptidase Inhibitor 1 86925
Fmoc
L
Siponimod
Taraxasterol mitigates Con A
Palmitoyl Tetrapeptide
N
cocaine use disorder
Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling PMID 30111653
Methylprednisolone acetate impurity 4 (Methylprednisolone impurity 21)
Carbendazimb
15
Targeted lipolysis for obesity treatment Cold atmospheric plasma
HCV
P
Isoflavonoid derivatives from Lophira alata stem heartwood PMID 21630581
PTEN deficiency sensitizes endometrioid endometrial cancer to compound PARP
Antioxidant capacity of flavonoids in hepatic microsomes is not reflected by antioxidant effects in vivo PMID 22919437
O1918 536697
Targeting JNK pathway promotes human hematopoietic stem cell expansion PMID 30622738
TNKS
Factor D Inhibition Blocks Complement Activation Induced by Mutant Factor B Associated With Atypical Hemolytic Uremic Syndrome and Membranoproliferative Glomerulonephritis PMID 34177949
The intracellular agent of Q fever, Coxiella burnetii, alters human alveolar macrophage metabolism and mitochondrial physiology PMID 40823830
PLLA6000
Zingerone attenuates concanavalin A
Isoliquiritigenin alleviates LPS/ D
Drisapersen 1251830
Ciprofloxacin impurity 1 (Ciprofloxacin impurity C)
m6A methylation modulates adipogenesis through JAK2
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin PMID 40705882
Characterization of SM201, an anti
Naproxen impurity 6 (Naproxen Nitrile impurity)
Synthesis of a substance P antagonist with a somatostatin scaffold factors affecting agonism/antagonism at GPCRs and the role of pseudosymmetry PMID 11052787
High
Fmoc
α
2
Eicosapentaenoic Acid sodium 73167
Birthweights in the Faroe Islands possible role of isovaleric acid PMID 2646392
Inhibition of saturated very
Silafluofen (氟硅菊酯)
PP30 1092788
Efipladib 381683
Melatonin Balance the Autophagy and Apoptosis by Regulating UCP2 in the LPS
Human Serum Albumin
SRFBP1 蛋白, Human (sf9, His
Fmoc
Mardepodect hydrochloride 2070014
Long noncoding RNA (lncRNA) EIF3J
microRNA
Spinal interleukin
Antimalarial activity of a combination of 5
177Lu
Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression PMID 40366632
JNJ
DOPE
L
Daphnane Diterpenoids from Daphne genkwa Inhibit PI3K/Akt/mTOR Signaling and Induce Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells PMID 32223193
H2
Discovery and Optimization of Tetrahydroisoquinoline Derivatives To Enhance Lysosome Biogenesis as Preclinical Candidates for the Treatment of Alzheimer's Disease PMID 38830007
OBI
Immune monitoring
(15R)
Rapid 3D printing of functional nanoparticle
Endo
SARS
RC574 2584411
MCE
(RS)
Methyl 2
Homo
Thialysine hydrochloride 4099
Azerutamig 2920336
Senicapoc 289656
Tetrahydroalstonine 6474
Contrasting intra
BRD5648 2056261
Tn5 Transposase 308064
ACVR2B 蛋白, Human/Cynomolgus (Biotinylated, HEK293, mFc)
Vonedrine
KST012174 hydrochloride
H
(S)
Insight into anti
Diethylstilbestrol
PLLA6000
Shengqiyichang decoction regulates antitumor immunity in colorectal cancer by downregulating lymphocyte antigen 6 family member G6D via the protein kinase B/p38 mitogen
hsa
The interaction of coumarin antibiotics with fragments of DNA gyrase B protein PMID 8664301
Kaempferol 3
Inhibition of Pseudomonas aeruginosa Carbonic Anhydrases, Exploring Ciprofloxacin Functionalization Toward New Antibacterial Agents An In
(2R,3R)
MSC2530818 1883423
D
mmu
10
Pyrotinib (Standard) (吡咯替尼 (标准品))
Amlodipine impurity 8 (Amlodipine impurity 31)
8,9
MCE
Mirror
Ultrasound Imaging of Tumor Vascular CD93 with MMRN2 Modified Microbubbles for Immune Microenvironment Prediction PMID 38270289
Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3
ORM
Olopatadine 113806
Lurasidone
FEN1
Synthesis, anti
endo
PROTAC K
BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT
Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization PMID 34463764
MCE
Daphnetin ameliorates PM2.5
TMB
Depiperazine
Lubiprostone prevents nonsteroidal anti
Targeting human Mas
H
Cannabinoids Reduce Extracellular Vesicle Release from HIV
Discovery of novel thiophene derivatives as potent neuraminidase inhibitors PMID 34411893
ACTR1B 抗体 (YA5956)（ACTR1B Antibody (YA5956)）
Novel Chemicals Derived from Tadalafil Exhibit PRMT5 Inhibition and Promising Activities against Breast Cancer PMID 35563196
G 蛋白亚基γ13（GNG13）基因
Win 18446 1477
Myriatic effect of 9
IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon
MPI
Butylated hydroxytoluene
Effects of Ire1 gene on virulence and pathogenicity of Candida albicans PMID 40321158
Palmitoyl serotonin 212707
RKI
Repetitive Transcranial Magnetic Stimulation Alleviates MPTP
NSC
胰岛素（INS）基因
Synthesis and biological activities of indolactone
Octopamine terminates sex pheromone biosynthesis by suppressing PBAN signal in moths PMID 35652818
MCE
Igsf11 Mouse Pre
KT182 1402612
Salmeterol impurity 1 (Salmeterol impurity A)
Tipifarnib (Standard) (替吡法尼 (标准品))
Human Serum Albumin
N
Tetrahydropapaverine hydrochloride 6429
PLLA8000
Stachartin C 1978388
R162 (Standard)
Angpt4 Mouse Pre
Phosphodiesterase
磷酸肌醇 3 激酶相互作用蛋白 1（PIK3IP1）基因
AR
Z
(±)
Endothall 145
SD
Mal
Contribution of microRNA
Smurf1 polyubiquitinates on K285/K282 of the kinases Mst1/2 to attenuate their tumor
Digitoxin inhibits ICC cell properties via the NF‑κB/ST6GAL1 signaling pathway PMID 38940341
Discovery of A
Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor
Cancer associated fibroblasts
Prostaglandin D2 41598
Design and characterization of a novel tumor
PP2A alpha/beta 抗体 (YA6103)（PP2A alpha/beta Antibody (YA6103)）
Glyr1
Long
Nobiletin enhances the development and quality of bovine embryos in vitro during two key periods of embryonic genome activation PMID 34083641
DL
VPC 23019 449173
H
BAY
Overcoming multi
t
地克珠利
Igkc siRNA
Design, synthesis and evaluation of diarylpiperazine derivatives as potent anti
Asah2 Rat Pre
GW856464 851690
Ethyl 3
H
PLLA1000
MC
Identification of new 4
Rhapontigenin 3'
Effect of the lipid chain melting transition on the stability of DSPE
Lofexidine hydrochloride 21498
Anticancer agent 103 2914922
Tauroursodeoxycholate
Alagebrium chloride 341028
Pterosin Z 34169
Fmoc
Cy3 labled IONIS
Epalrestat 82159
In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram
Crystal structure of the Homo sapiens kynureninase
2
Feigrisolide B 313949
PTBP1 knockdown promotes neural differentiation of glioblastoma cells through UNC5B receptor PMID 35664063
N2,N6
Eprotirome 355129
Boc
L 640035
1,4
Novel fully human high
HAUS1 Human Pre
Danoprevir sodium 916826
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors PMID 9677190
GNE
Porphyromonas gingivalis induced up
Safety and activity of WX
YPC
FR
Met
6
p38α inhibitor 5 2550397
Studies on cytotoxic constituents from the leaves of Elaeagnus oldhamii Maxim. in non
Trelanserin 189003
SB
Repulsive guidance molecule A 抗体 (YA6945)（Repulsive guidance molecule A Antibody (YA6945)）
TIM
Myricanol 33606
Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple
[Inhibitory effects of Spartina anglica on Heterosigma akashiwo and Prorocenrum micans and the isolation and identification of the algicidal compounds] PMID 20077720
Design, synthesis and in vitro biological evaluation of novel [1,2,3]triazolo[4,5
Mono(2
BMS
Royleanonic acid 350590
Small
AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin
CWC15 Human Pre
MSOP (Standard)
Isoscutellarein 8
Metabolism of the Fusarium Mycotoxins T
Antiparasitic agent
(Rac)
Connectivity mapping
PLLA1000
IU1
NE58043 105462
Paraventricular hypothalamic input to anterior cingulate cortex controls food preferences in chronic visceral pain mice PMID 40593837
2
Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats PMID 27417257
Synthesis, molecular modeling and biological evaluation of N
Vsig1 Mouse Pre
H
SP
Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ
Nicomol 27959
Br
BBR 2160 118587
SR10067 1380548
MCCC2 is a novel mediator between mitochondria and telomere and functions as an oncogene in colorectal cancer PMID 37828426
burn injury model
Cinnamyl
Ki
Cinnamyl coumarate (Coumaric acid cinnamyl ester，香豆酸肉桂酯)
SARS
inorganic phosphorus
Inhibition of PHB1/PHB2 suppresses atherosclerotic plaque formation by interrupting PI3K/AKT/mTOR signaling PMID 40168274
MCE
L
GM
Efavaleukin alfa
Vanillactic acid (VLA)
Acrolein Aggravates Secondary Brain Injury After Intracerebral Hemorrhage Through Drp1
Curcumin enhances ATG3
Identification of the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N
含 SH2 域 3C（SH2D3C）基因
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis PMID 32561730
Structure and function of plant acyl
Interferon gamma
BION106 3077918
Structural basis of stepwise proton sensing
Cyclin B1 抗体 (YA3794)（Cyclin B1 Antibody (YA3794)）
Trk pan 抗体 (YA5939)（Trk pan Antibody (YA5939)）
Antibody
Fluorescent quenching
诺斯卡品
Sorbs2 regulates seizure activity by influencing AMPAR
Ephrin
PGRMC1 Human Pre
Iloprost affects in vitro maturation and developmental competence of bovine oocytes PMID 32823024
uPAR 蛋白, Mouse (Biotinylated, HEK293, His
Sulfo
Fadrozole hydrochloride hemihydrate 176702
Non
Synthesis, anticancer and antioxidant activities of 2,4,5
A new polyoxygenated cyclohexene and a new megastigmane glycoside from Uvaria grandiflora PMID 26077495
SRP9 Human Pre
Clofazimine an old drug for never
PEG3
L
Sec
Novel 4
B4galt1
Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice PMID 33731795
GPR108 Human Pre
Linagliptin, a Selective Dipeptidyl Peptidase
Novel textile dye obtained through transformation of 2
Novel non
Disposition and metabolism of LY2452473, a selective androgen receptor modulator, in humans PMID 22961682
CD532 hydrochloride 2926498
Vtcn1 Rat Pre
Effects of Koumine on Adjuvant
MCE
PSMD1 Human Pre
Expression of Src and FAK in hepatocellular carcinoma and the effect of Src inhibitors on hepatocellular carcinoma in vitro PMID 18979199
16alpha
转录延伸因子 A 样 1（TCEAL1）基因
Antitubercular agent
A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1
Activation of the hypoxia
Mlana Mouse Pre
Puerarin reduces susceptibility to ventricular arrhythmias and inhibits ferroptosis via Sirt1/Nrf2 signaling in high
A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors PMID 30655555
Characterization of a novel bispecific antibody targeting tissue factor
Efficient episomal reprogramming of blood mononuclear cells and differentiation to hepatocytes with functional drug metabolism PMID 26256888
Synthetic polyamines added to cultures containing bovine sera reversibly inhibit in vitro parameters of immunity PMID 141619
Regulation of SPRY3 by X chromosome and PAR2
Effects of Irgacure 2959 and lithium phenyl
ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2
Combretastatin A
Design, synthesis and biological evaluation of novel histone deacetylase1/2 (HDAC1/2) and cyclin
Farnesol inhibits in vitro growth of the Cryptococcus neoformans species complex with no significant changes in virulence
PanK1抑制剂、基因
Tex264 Rat Pre
LOXL3 Human Pre
KCNF1 Human Pre
Enzyme
Structural Insights and Development of LRRK2 Inhibitors for Parkinson's Disease in the Last Decade PMID 36011337
Palmitanilide 6832
Dipyridamole enhances NO/cGMP
serpin 家族 B 成员 2（SERPINB2）基因
MCE
Diethyl phosphate
Oleylphosphocholine
BSI
Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein PMID 34862367
A Diacylglycerol Transferase 1 Inhibitor Is a Potent Hepatitis C Antiviral in Vitro but Not in Patients in a Randomized Clinical Trial PMID 27788579
HBX 19818 1426944
hsa
MCE
Parisyunnanoside B
PIPES sesquisodium
Sinefungin 58944
Fmoc
FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation PMID 29610484
DL
The selective intravenous inhibitor of the MET tyrosine kinase SAR125844 inhibits tumor growth in MET
Design and Characterization of Squaramic Acid
PRNP Human Pre
GSDME Increases Chemotherapeutic Drug Sensitivity by Inducing Pyroptosis in Retinoblastoma Cells PMID 35480866
Reproxalap 916056
Basophils produce IL
Electrophysiology
Cxcl10
Discovery of repurposed ethacrynic acid and its derivatives as novel TEAD inhibitors PMID 41161055
Bacterial biosensors for screening isoform
Acetic acid, 2
Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation PMID 16713429
Matrine attenuating cardiomyocyte apoptosis in doxorubicin
Screen for Inhibitors of STK33 Kinase Activity PMID 23658944
SB 216763
Lotusine 6871
TMEM16A Inhibition Preserves Blood
Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro
ALDH 9028
The beta
SHH Human Pre
EGFRvIII peptide
Corynoxine B 17391
CDK7
Analysis pipelines for calcium imaging data PMID 30529147
Modulating Protein
Simvastatin
Multi
Z
SLC37A2
Hemslecin A
CRBN ligand
Octadecane
MCE
Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells PMID 17332266
C1galt1
N
Structure
Kunitz
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