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AZ14145845 2830555
ZINC13000658 1324070
Dipyridamole
DMHCA 79066
Massoia lactone 54814
Mycobacterial tryptophan biosynthesis A promising target for tuberculosis drug development? PMID 31627992
Schizandriside 71222
Inhibition of cyclin E1 sensitizes hepatocellular carcinoma cells to regorafenib by mcl
Inhibition of CXCR4 in Spinal Cord and DRG with AMD3100 Attenuates Colon
(+)
UCM 549 753502
A human organoid drug screen identifies α2
3’
2
GaTx2 194665
eIF4E
Parallel single
m
Inhibitory effect of mannan on the toxicity produced in mice fed aflatoxin B1 contaminated corn PMID 17657450
Semi
BTNL2, a butyrophilin/B7
IRAK4
Inositol 1,4,5
Repurposing the Damage Repair Protein Methyl Guanine Methyl Transferase as a Ligand Inducible Fusion Degron PMID 34982531
Guanine nucleotide exchange factor RABGEF1 facilitates TNF
Selective androgen receptor modulators for the prevention and treatment of muscle wasting associated with cancer PMID 24189892
ARHGAP17 Inhibits Hepatocellular Carcinoma Progression by Inactivation of Wnt/β
Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF
5
Antiproliferative and antiplasmodial compounds from selected Streptomyces species PMID 26508548
EDA2R/XEDAR 蛋白, Human (HEK293, His)
Estradiol valerianate
BDP 12
The design of 1,4
Folr1 Mouse Pre
Lymphotoxin
Design, Synthesis, and Biological Evaluation of Selective PAK4 Degrader for the Treatment of Lung Tumor Metastasis PMID 40404481
Macrophage co
tert
Novel antiproliferative agents bearing morpholinopyrimidine scaffold as PI3K inhibitors and apoptosis inducers; design, synthesis and molecular docking PMID 32659486
Enrofloxacin
Sitagliptin impurity 27 767340
Hydroxyzine inhibits neurogenic bladder mast cell activation PMID 9839659
Bazlitoran (IMO
5
Delphinidin
2
G protein
Encorafenib (LGX818), a potent BRAF inhibitor, induces senescence accompanied by autophagy in BRAFV600E melanoma cells PMID 26586345
Ginkgolide K 153355
SARS
Morphology and axonal projection pattern of neurons in the telencephalon of the fire
dUTP
STK11 mutation affects the killing effect of NK cells to promote the progression of lung adenocarcinoma PMID 35988018
Chronic treatment with the gamma
Azelnidipine 123524
Chemoproteomic capture of RNA binding activity in living cells PMID 37805600
11
Silybin 802918
Ciwujianoside D1 114912
c
S6 peptide 93674
DPTE
OTU 去泛素化酶，泛素醛结合 1（OTUB1）基因
BTP9
Loganin reduces neuroinflammation and promotes functional recovery after spinal cord injury through inhibiting NF
Desloratadine PMID 11398910
Molecular basis for the regulation of human phosphorylase kinase by phosphorylation and Ca2 PMID 40148320
An orally available, small
BTK
NVS MLLT
Nav1.7
Timegadine 71079
Gilvocarcin M 77879
4
PROTAC CRBN Degrader
NK cell recognition PMID 15771571
Tenofovir impurity 8 (Tenofovir impurity M)
Catalpalactone 1585
Cardiovascular effects of angiotensin A a novel peptide of the renin
Glycine alleviates fluoride
1
CRBN ligand
含三方基序 25（TRIM25）基因
Premafloxacin
Do Nanoparticles of Calcium Disodium EDTA Minimize the Toxic Effects of Cadmium in Female Rats? PMID 37721680
Mechanism of pro
MCE
Retracing from Outcomes to Causes NRF2
Nervogenic acid 17622
KTC1101 2764833
Heme oxygenase
Synthesis, Biological Evaluation, and Molecular Docking of Arylpyridines as Antiproliferative Agent Targeting Tubulin PMID 32832031
Inhibition of the Na,K
ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity PMID 40166327
Echinococcus granulosus cyst fluid inhibits the type I interferon response by promoting ROS in macrophages PMID 38101763
MCE
CYP2S1 Human Pre
A novel strategy to block mitotic progression for targeted therapy PMID 31669221
Integrating network pharmacology to investigate the mechanism of quercetin's action through AKT inhibition in co
L
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4
The ex vivo antiplatelet activation potential of fruit phenolic metabolite hippuric acid PMID 26137920
Levodropropizine reduces capsaicin
Identification and biological characterization of 6
Liver X Receptor Ligand GAC0001E5 Downregulates Antioxidant Capacity and ERBB2/HER2 Expression in HER2
High expression of serine protease inhibitor kazal type 1 predicts poor prognosis and promotes the progression and invasion of oral tongue squamous cell carcinoma PMID 38781741
Simvastatin impurity 1
Methyl 9(S),10(S)
TNFα blockade overcomes resistance to anti
VEGFR
Protective Effects of Imatinib on a DSS
IGKC Human Pre
SEC61G promotes colorectal cancer progression by regulating cytosolic Ca2+ concentration PMID 40413702
MCE
Tribenuron 106040
Discovery of coumarin
SPG11 Human Pre
Oxiran
Erythrosine B aluminum 12227
厚叶岩白菜提取物 (Bergenia crassifolia (L.) Fritsch)
Pdk4 Mouse Pre
Effects of electromagnetic pulses, exosomes inhibition and their coaction on A549 cells PMID 38533693
MCE
PUMA 抗体 (YA116)（PUMA Antibody (YA116)）
Design, Synthesis, and Biological Evaluation of Potent FLT3 Inhibitor for Acute Myeloid Leukemia (AML) Treatment PMID 40534276
Cytosine
Inhibitory mechanism of Korean Red Ginseng on GM
JNJ
Tabimorelin 193079
Setdb1 protects genome integrity in murine muscle stem cells to allow for regenerative myogenesis and inflammation PMID 38848717
BDNF 蛋白, Human (R125A, R127A, R128A)
Effects of disulfide bond and cholesterol derivatives on human calcitonin amyloid formation PMID 31804717
6β
Aceprometazine 13461
MitoPBN 652968
2
Tubotaiwine 6711
Tetranor
KP
Pyrene
PIK3CA and CCM mutations fuel cavernomas through a cancer
mmu
Dusquetide A novel innate defense regulator demonstrating a significant and consistent reduction in the duration of oral mucositis in preclinical data and a randomized, placebo
Fmoc
Surlorian 1467605
Sustained exposure to Helicobacter pylori induces immune tolerance by desensitizing TLR6 PMID 38310631
Topical application of phenformin ameliorates the psoriasis
内酰胺酶 2（LACTB2）基因
Varenicline crbamoyl β
Coptisine chloride 6020
FAM3B
Interaction of Insulin
Lintopride hydrochloride 268548
DHFR
α
Structures of artificial sweeteners
Imbalance in the estrogen/androgen ratio may affect prostate fibrosis through the TGF
3
MI
Boc
Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening PMID 31756401
4
MCE
Discovery of adamantane
Fenirofibrate impurity 6 42019
Meclozine
CB2R/FAAH modulator
Lead compounds for the development of SARS
(
C
β
Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis PMID 33186519
(3R,5S)
PDK1
Comparative Proteomics Unveils LRRFIP1 as a New Player in the DAPK1 Interactome of Neurons Exposed to Oxygen and Glucose Deprivation PMID 33265962
Primary and secondary structure of novel ACE
L
Mcl
5
Kuwanol C
Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance PMID 17970756
Unzippable Siamese Nanoparticles for Programmed Two
Magnetic nanoparticles coated with carbohydrates for 3D culture of bacteria PMID 32806306
Α
JNJ
4
gamma
Methyl 4
YKL
Klebsiella pneumoniae induces inflammatory bowel disease through caspase
CRBN ligand
Matrix solid
Acetyl
β
Mechanisms of Bushen Tiaoxue Granules against controlled ovarian hyperstimulation
LY300503 148905
Synthesis and antiviral evaluation of 6
Synthesis and evaluation of novel tetrahydroisoquinoline
Lulizumab 2235419
Precise CRISPR
solid malignancies
Dose
Flavokawain A
Tetrahydroalstonine from Fruits of Rhazya stricta PMID 17340319
5'
Meloxicam Alleviates Oxidative Stress Through Nrf2/HO
T24
mouse chondrocytes
anticarcinogenic
PAK
STL127705 1326852
nonsteroidal
Bz
EJ cells
chalcone
CH1055
Multi
progesterone
SF
PF
In vitro Toxicity and in vivo Immunomodulatory Effects of Flavokawain A and Flavokawain B in Balb/C Mice PMID 26411010
N
Histone Methyltransferase
Adamantane derivatives as potential inhibitors of p37 major envelope protein and poxvirus reproduction. Design, synthesis and antiviral activity PMID 33965861
H1299 cells
CER6
Tnfsf4
An update on carbonic anhydrase
寡糖转移酶复合物非催化亚基（OSTC）基因
Surgestone
High
GCGR
R
Flavokawain A 3420
Human and Zebrafish Nuclear Progesterone Receptors Are Differently Activated by Manifold Progestins PMID 32650635
glucagon
Biotin amelioration of nephrotoxicity in streptozotocin
Common names of pesticides recently approved by the BSI PMID 12639057
HELN
DNA
U2OS
UEA I (Biotinylated)
FC382K10W15
Murine ZP3 peptide (330
A novel small molecule inhibitor of the DNA repair protein Ku70/80 PMID 27130816
Ulex Europaeus Agglutinin I (Biotinylated)
Promegestone 34184
Excess intracellular ATP causes neuropathic pain following spinal cord injury PMID 35972649
Preclinical and clinical pharmacokinetics of PF
The translational efficacy of a nonsteroidal progesterone receptor antagonist, 4
PF
5
Posttranslationally modified progesterone receptors direct ligand
Fibroblast growth factor receptor (FGFR) 4 correlated with the malignancy of human astrocytomas PMID 11958417
HELN
Adrenergic Receptor
Slc39a6
PTPRS
TNFSF4
TNFSF4
J 104129 fumarate 257603
PAK2 Human Pre
Hydroxy
FOSL2 activates TGF
TNFSF4
TNFSF4
DMT
CXCR4
Identification of non
5
Effect of butyrolactone I on the producing fungus, Aspergillus terreus PMID 9758788
Nitric oxide
Synthesis and molecular modelling of unsaturated exomethylene pyranonucleoside analogues with antitumor and antiviral activities PMID 18037195
OX40 Ligand/TNFSF4 蛋白, Mouse (HEK293, hFc)
Ogdh Rat Pre
HMGB1 contributes to pancreatic fibrosis by regulating TLR4
RAB14，RAS 致癌基因家族成员（RAB14）基因
Citrinin exposure affects oocyte maturation and embryo development by inducing oxidative stress
Alpha
M1‑like tumor‑associated macrophages enhance proliferation and anti‑apoptotic ability of liver cancer cells via activating the NF‑κB signaling pathway PMID 36069218
Alborixin clears amyloid
Vildagliptin
Design, synthesis and biological evaluation of novel 4
Ethyl decanoate
Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti
Identification of vitamin d3
Niemann Pick C2/NPC2 蛋白, Human (HEK293, His)
Gemin D 84744
(S,S,S)
Cholesterol
Propargyl
CRBN ligand
Ferrozine sodium hydrate 1266615
Oxidized soluble guanylyl cyclase causes erectile dysfunction in alcoholic mice PMID 37021655
Neuroprotective Effects of Spinosin on Recovery of Learning and Memory in a Mouse Model of Alzheimer's Disease PMID 29925225
FASTKD2 Human Pre
HA1/Hemagglutinin 蛋白, H5N1 (ABD28180, HEK293, His)
Boosting Hydroxyl Radical Generation with Nitrogen Vacancy
Fmoc
CHK1
Synthesis, Structure
Determination of the new monoamine oxidase inhibitor moclobemide and three of its metabolites in biological fluids by high
KRCA
(R)
Targeting breast cancer cells by MRS1477, a positive allosteric modulator of TRPV1 channels PMID 28640864
STAT3
Anivovetmab 2370896
IDH2R140Q
DRD1 agonist A
Knockout of secretin receptor reduces large cholangiocyte hyperplasia in mice with extrahepatic cholestasis induced by bile duct ligation PMID 20578263
Design, synthesis and biological evaluation of indolin
Apafant, a potent platelet
Gnetum montanum extract induces apoptosis by inhibiting the activation of AKT in SW480 human colon cancer cells PMID 35587342
APS03118 2598870
JNJ
NSC
The Long
CP
Long non
CDK2/4 ligand 1 1211585
Nile Blue A sulfate (Nile blue sulfate，硫酸耐尔蓝A;硫酸尼罗蓝;硫酸耐尔蓝)
PP121 (Standard)
BFH772 (Standard)
Sitagliptin impurity 11
Sitagliptin impurity 18
Serum amyloid A aggravates endotoxin
JAK
Simvastatin impurity 12
Inhibition of the Ras
Pro
Cspg5 Rat Pre
Sitagliptin impurity 20
MASTL
Rotundine 483
GSK2879552 dihydrochloride 1902123
Salicylic acid
P4
AcLysValCit
Empagliflozin attenuates inflammation levels in autoimmune myocarditis through the STAT3 pathway and macrophage phenotype transformation PMID 38354482
BNP(1
DW14006 as a Direct AMPKα Activator Ameliorates Diabetic Peripheral Neuropathy in Mice PMID 32647036
Phenmedipham 13684
2
Metformin accelerates bone fracture healing by promoting type H vessel formation through inhibition of YAP1/TAZ expression PMID 37587136
Diayangambin exerts immunosuppressive and anti
Gallopamil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in ischaemic heart disease PMID 7510624
Donepezil impurity 9 2452407
覆盆子酮
4
Diclofenac impurity 8 22121
4
SU5408 (Standard)
EP300/CREBBP induces osteogenic differentiation of valve interstitial cells by promoting the SPP1 expression in calcific aortic valve disease PMID 40873695
Discovery of ERD
BODIPY 576/589 150173
(S)
Wnt16 signaling promotes osteoblast differentiation of periosteal derived cells in vitro and in vivo PMID 33282557
Exatecan Intermediate 7 182182
Competitive Binding Assay with an Umbelliferone
Promoting Re
LINC00525 promotes tumour growth and epithelial
Verteporfin 129497
RACGAP1 knockdown synergizes and enhances the effects of chemotherapeutics on ovarian cancer PMID 38883382
RIPK2
6
QSH peptide 470459
Tiagabine
ICMT
Leukotriene E4
Alpha
Cdc42 regulates Fc gamma receptor
Mito
β
NLRP3
Levodropropizine suppresses seizure activity in rats with pentylenetetrazol
Therapeutic options for acute cough due to upper respiratory infections in children PMID 21892785
2
HX1 1520083
CDK1
FAP
Human CDK18 promotes replication stress signaling and genome stability PMID 27382066
Tempol, a membrane
A chemically controlled Cas9 switch enables temporal modulation of diverse effectors PMID 36879061
Feruloyl tyramine 65646
Tubulin inhibitor 6 105925
2R,4S
Gynostemma pentaphyllum Hydrodistillate and Its Major Component Damulin B Promote Hair Growth
D
Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis PMID 37843554
The effect of oxamflatin on the E
Pan
Simvastatin impurity 2 sodium
Val
Microbiota
Functionalized Phenylbenzamides Inhibit Aquaporin
Simvastatin impurity 8
Simvastatin impurity 5 ((3S,5S)
Simvastatin Hydroxy Acid Sodium Salt
2'
Studies in the biochemistry of micro
Phospholipase C
Dopal 5707
PD
Methyl 2
Inhibiting the JNK Signaling Pathway Attenuates Hypersensitivity and Anxiety
1H
MCE
蜂窝通信网络因素 3（CCN3）基因
Polystyrene nanoparticle exposure supports ROS
SND1 aggravates mitochondrial damage, apoptosis and extracellular matrix degradation in IL
(2Z,3Z)
MCE
9(S)
Apoptosis inducer 19 3049296
(+)
Acetyl
BOC
KIF18A
Nicotinamide Phosphoribosyltransferase Positive Allosteric Modulators Attenuate Neuronal Oxidative Stress PMID 38352833
Perezone and its phenyl glycine derivative induce cytotoxicity via caspases on human glial cancer cells PMID 37341748
PLK1
Monoamine oxidase B inhibits epithelial
Guanine (Standard)
Tmx3 Rat Pre
(S)
hsa
Synthesis and biological evaluation of novel benzylidene
PROTAC EML4
ROCK1/2 signaling contributes to corticosteroid
FFN270 hydrochloride 2341841
Small extracellular vesicles derived from human mesenchymal stem cells prevent Th17
14
ZMC2
4
The plant terpenes DMNT and TMTT function as signaling compounds that attract Asian corn borer (Ostrinia furnacalis) to maize plants PMID 39171839
5
Difloxacin
Antibody engineers seek optimal drug targeting TIGIT checkpoint PMID 32887966
Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe PMID 2751699
N6
Safety evaluation of disodium 5'
Direct and specific binding of cholesterol to the mitochondrial translocator protein (TSPO) using PhotoClick cholesterol analogue PMID 33846725
Oroxylin A Suppresses the Cell Proliferation, Migration, and EMT via NF
TG
Potent in vitro and in vivo activity of an Fc
Alginate Oligosaccharides Protect Gastric Epithelial Cells against Oxidative Stress Damage through Induction of the Nrf2 Pathway PMID 38790723
EGFR
Farnesoid X receptor
(4S)
UNC1021 1322591
Dopamine
HSP70 protects PC12 cells against TBHP
OX40 Ligand/TNFSF4 蛋白, Rabbit (HEK293, His)
Restoration of SIRT3 Expression in Aged Mice Alleviates UUO
Arg
7
Bivamelagon 2641595
NL
γ
4
Ceforanide 60925
Brefonalol 103880
Regulatory Effects of Zhenxin Formula in Treating Doxorubicin
CNPY2 蛋白, Human (HEK293, His)
抑制剂
Avapritinib 1703793
MCE
LEI
hsa
Ogdh Mouse Pre
NYX
MCE
L
SSR180575 220448
Amino
The reactivity of desmosterol and other shellfish
5
Peptide density targets and impedes triple negative breast cancer metastasis PMID 29973594
Carboxy finasteride 116285
Beta vulgaris
Control of motor coordination by transient receptor potential melastatin 8 through γ
Typhaneoside 104472
Astragaloside IV restores Th17/Treg balance via inhibiting CXCR4 to improve chronic obstructive pulmonary disease PMID 37417915
N
Pyrroside B 116271
NCTT
OMJ
Bioactive Iridoid Glycosides from the Whole Plants of Rehmannia chingii PMID 26859776
Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol PMID 2897122
Santonin
Zardaverine a cyclic AMP specific PDE III/IV inhibitor PMID 1665311
Octyl 4
OSU
Methyl 12(R),13(S)
MDA MB
Austdiol 53043
ASL 279
Omiganan
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