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Synthesis of new lophine
Melatonin reverses lenvatinib resistance in HCC by regulating the ATF4
TSAO
15
Ad
The Discovery of a Specific CKIP
The research progression of direct NLRP3 inhibitors to treat inflammatory disorders PMID 38324950
Protective Effect of Resveratrol against Hypoxia
PDE4
Hexaconazole 79983
HIV
(3S)
MERS
[Clinical study of an antispasmodic with a predominantly musculotropic action 2
2
(R)
(R)
Aberrant gene activation in synovial sarcoma relies on SSX specificity and increased PRC1.1 stability PMID 37735617
YBX1 蛋白, Human (His)
(S)
IDH1 蛋白, Human (R132C, His)
Preclinical development of ozuriftamab vedotin (BA3021), a novel ROR2
PYR
Fragment Binding to the Nsp3 Macrodomain of SARS
SARS
Effect of spironolactone and its main metabolite canrenone on the renin
BIX
Improved Processing and Properties for Polyphenylene Oxide Modified by Diallyl Orthophthalate Prepolymer PMID 31817390
Eliroptamig
RDEA 806 878670
Liquid chromatography
GSK215 2743427
Crenolanib inhibits the drug
Amuvatinib 850879
Fluzoparib 1358715
SLN
Amanozine 537
Anticancer agent 122 2924532
HA/Hemagglutinin 蛋白, H1N1 (ABF21274, sf9, His)
SR
Phenyl α
NFKB 抑制因子 α（NFKBIA）基因
Synthesis of Heterocyclic Ring
成纤维细胞生长因子受体 4（Fgfr4）基因
Sitagliptin impurity 23
Xanthine oxidase
METTL3 alters AK3 RNA expression in an m6A
Redox
hsa
Nonan
GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis PMID 38636926
PI3K
Quinoline
BET
Leptin promotes tendon stem/progenitor cell senescence through the AKT
Quebecol 1360605
Synthesis of Novel (S)
Dabsyl chloride 56512
Aurantiogliocladin
Meta
Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448) PMID 36518696
Structure
Zilganersen sodium 2305355
SUMO2 蛋白, Human (His)
Folate receptor mediated intracellular protein delivery using PLL
白细胞介素 15（IL15）基因
CDC
PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza PMID 16141564
4,4'
Estradiol Valerate impurity 2 1350468
Vitamin D receptor agonist doxercalciferol modulates dietary fat
CDK4/6
The WNT5A Agonist Foxy5 Reduces the Number of Colonic Cancer Stem Cells in a Xenograft Mouse Model of Human Colonic Cancer PMID 30952711
BMS
Discovery and optimization of new benzimidazole
Single
Clomipramine hydrochloride 17321
1,3
Sodium dodecanoate, 99
Branched
TNFSF4 Human Pre
First evidence of the possible implication of the 11
N
Three Ingredients of Safflower Alleviate Acute Lung Injury and Inhibit NET Release Induced by Lipopolysaccharide PMID 32189992
Lck
Hepatoprotective agent
Sodium
无名指蛋白 126（RNF126）基因
The nicotinic alpha 4 beta 2 receptor selective agonist, TC
D
Imiprothrin (炔咪菊酯)
Masofaniten 2416716
M
NSC11
CYP7A1 抗体 (YA5117)（CYP7A1 Antibody (YA5117)）
Cinacalcet hydrochloride 364782
Actinocrispum wychmicini gen. nov., sp. nov., a novel member of the family Pseudonocardiaceae, isolated from soil PMID 27535579
ALPN 101
Rbm14 Rat Pre
(Met(O)35)
liver microsome
Discovery of 4
IDEC
SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway PMID 31406106
SSGJ
Cspg5 Mouse Pre
Chrysin attenuates progression of ovarian cancer cells by regulating signaling cascades and mitochondrial dysfunction PMID 28816359
GS
OGDH Human Pre
Sitagliptin impurity 14
MeCP2
TP
Biological activities and pharmacokinetics of aconitine, benzoylaconine, and aconine after oral administration in rats PMID 26360128
BA 1 183241
Identification, characterization and application of a new peptide against anterior gradient homolog 2 (AGR2) PMID 29937991
ringworm
[Glu27]
Polyketide synthase 13
Thifensulfuron
MARCH2, a T cell specific factor that restricts HIV
BMS
Synthesis, Antiplasmodial Activity, and β
SSAO/VAP
Fmoc
Calothrixin B by docking JAK2 is a potential therapeutic inhibitor for pancreatic ductal adenocarcinoma PMID 39847514
Rivaroxaban impurity 6 (Standard)
Widespread occurrence and accumulation of bisphenol A diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE) and their derivatives in human blood and adipose fat PMID 25679329
Characterization of 5(6)
Azido
Stabilization of ERK
HY
The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro PMID 16331496
Discovery of 2
Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin
Constitutive photomorphogenic protein 1 ubiquitinates interleukin
Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway PMID 12904460
IRG1/itaconate enhances efferocytosis by activating Nrf2
MIP
Daphnilongeranin C 750649
MCE
VER
Musk
NSC 663284 (Standard)
BRCA1
ZL006 (Standard)
Alrizomadlin (Standard)
Human thrombospondin
Preclinical Characterization of ARX517, a Site
HTS01037 (Standard)
SCAMP3 Regulates EGFR and Promotes Proliferation and Migration of Triple
Tetrandrine alleviates macrophage activation syndrome after CAR
Phenolic metabolite profiles and antioxidants assay of three Iridaceae medicinal plants for traditional Chinese medicine She
Small molecules for interference with cell
Structure
PF
PQBP1 Human Pre
Phase I study of GSK461364, a specific and competitive Polo
[In vitro development of rifampicin resistance in the epithelial cells] PMID 17002061
Bavachin 19879
PROTAC STAT6 degrader
Angiotensin II (3
Lunlekitug 2640257
Annexin 1
(S)
Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol PMID 12231565
Non
SARS
Thiol
Flavonoids from the leaves of Epimedium Koreanum Nakai and their potential cytotoxic activities PMID 30663372
(1R,2S)
Vinaginsenoside R2
LY379268 (Standard)
Telomerase reverse transcriptase degradation via a rationally designed covalent proteolysis targeting chimera PMID 40412449
Aluminum exposure induces nephrotoxicity via fibrosis and apoptosis through the TGF
Thromboxane A(2) regulation of endothelial cell migration, angiogenesis, and tumor metastasis PMID 10623605
BMS
Magnesium supplementation enhances mTOR signalling to facilitate myogenic differentiation and improve aged muscle performance PMID 33592327
Demethyl Benzydamine
Trifluperidol hydrochloride 2062
AP Endonuclease 1 as a Key Enzyme in Repair of Apurinic/Apyrimidinic Sites PMID 27682167
Allosteric Inhibition as a New Mode of Action for BAY 1213790, a Neutralizing Antibody Targeting the Activated Form of Coagulation Factor XI PMID 31655039
Sitagliptin impurity 19
Models of protein modification in Tris
Erythrocytes
Enantioselective Degrader for Elimination of Extracellular Aggregation
AU1235 (Standard)
ITGAV
Bowman
BSJ
Gateways to clinical trials PMID 17922073
Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum PMID 26946378
C.I. Acid blue 40 sodium salt 6424
The BRD4 Inhibitor dBET57 Exerts Anticancer Effects by Targeting Superenhancer
The anti
MCE
Structure
Lansoprazole pharmacokinetics in subjects with various degrees of kidney function PMID 9129562
paramyxovirus CD
SKF 81297 71636
Viomycin 32988
CRBN ligand
MCE
tert
CMI977 175212
Simultaneous quantification of ten Amadori compounds in tobacco using liquid chromatography with tandem mass spectrometry PMID 27987265
New Tools for Cryptosporidium Lead to New Hope for Cryptosporidiosis PMID 28750950
Vapendavir
Pentetreotide 138661
Etiprednol dicloacetate (BNP 166)
The metabolic effect of dodecanedioic acid infusion in non
Discovery of TAK
Expression, purification and reconstitution of the C
Montirelin 90243
Inhibition of glycogen breakdown by imino sugars in vitro and in vivo PMID 14757169
NXP800 1693734
CRBN ligand
Human mast cells arise from a common circulating progenitor PMID 23582567
MCE
candidate
Intracellular activation of SGN
Further synthetic and biological studies on vitamin D hormone antagonists based on C24
(D
URB447 1132922
1,5
Potassium 1H
LncRNA LINC00942 promotes chemoresistance in gastric cancer by suppressing MSI2 degradation to enhance c
Ameloblastin 蛋白, Human (HEK293, His)
BCAT2 蛋白, Human
Splicing modulation
果糖双磷酸酶 2（FBP2）基因
WNK3
Endo
LEFTY2
AM0001
UTA1inh
A time window for memory consolidation during NREM sleep revealed by cAMP oscillation PMID 40233747
MCE
G202
T
溶质载体家族 30 成员 3（SLC30A3）基因
79161
脱嘌呤/脱嘧啶脱氧核糖核酸内切酶 2（APEX2）基因
含 CKLF 样 MARVEL 跨膜结构域 7（CMTM7）基因
Benzyl N1
Sitagliptin impurity 7
AZ 12488024 1018988
mal，T 细胞分化蛋白 2（MAL2）基因
Baicalin suppresses macrophage JNK
Methylophiopogonone B
IL
REDIC1
9,9
Benzyl
Folate
Cyflumetofen 400882
前柴胡皂苷H
Aripiprazole Lauroxil 1259305
L07
Azukisaponin VI 82801
五味子酯丁
Chrysospermin C
CCR5 antagonist 5 869725
Lys
Tiropramide 55837
Protective effects of dimethyl itaconate in mice acute cardiotoxicity induced by doxorubicin PMID 31376936
Schisandrin A and B affect the proliferation and differentiation of neural stem cells PMID 34896558
(2S,4S)
ZD
6,7
Explorations of novel pyridine
Smart delivery of antisense oligonucleotides by anionic pH
Sitagliptin impurity 25
Drosophila tweety facilitates autophagy to regulate mitochondrial homeostasis and bioenergetics in Glia PMID 37870193
Cytotoxic and Antioxidant Properties of Natural Bioactive Monoterpenes Nerol, Estragole, and 3,7
Seco
Sitagliptin impurity 17
Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC
VEGF120 蛋白, Mouse (HEK293)
Thiol
Z
The binding specificity and selective antagonism of vedolizumab, an anti
Sappanone A 102067
CRTC3 Human Pre
Bitter taste TAS2R14 activation by intracellular tastants and cholesterol PMID 38776963
A Comparative Study on the Role of Polyvinylpyrrolidone Molecular Weight on the Functionalization of Various Carbon Nanotubes and Their Composites PMID 34372050
Animal
AHR
FGFR
HA/Hemagglutinin 蛋白, H1N1 (ABF21274, HEK293, His)
Subchronic exposure to CeCl3 promotes macrophage ferroptosis and atherosclerotic plaque formation by inhibiting the Keap1/Nrf2/GPX4 pathway PMID 40706741
hsa
Fisetin
CDK1
Idelalisib
Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes PMID 2536956
Hypophyllanthin 33676
1
Hydroxychloroquine modulates metabolic activity and proliferation and induces autophagic cell death of human dermal fibroblasts PMID 19357706
The active ingredients of Jiang
CRBN ligand
Coumarin 343 X NHS ester 946123
Bromperidol hydrochloride 59453
2,6
(2
Sulfo
FGFR
Ibutamoren Mesylate 159752
Amidate Prodrugs of Deoxythreosyl Nucleoside Phosphonates as Dual Inhibitors of HIV and HBV Replication PMID 27748590
PND
Cholyl
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK PMID 36217034
1,2
Genetic toxicity of 2
NLRP3
具有 ITAM 基序 1 的 NFAT 激活蛋白（NFAM1）基因
UK 55444
CHIR
1
嘌呤能受体 P2X 1（P2RX1）基因
RAB37，RAS 致癌基因家族成员（RAB37）基因
RSPO1/R
LY88074 177744
Lefty2 Rat Pre
Igkc Mouse Pre
Igkc Rat Pre
Phase II clinical trial of SKI
Circular RNA circ
MCE
PLK1/PRC1
Ranitidine impurity 4 15433
Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3
Guaiapate (Klamar，愈创哌特)
Threonine
Kadsurin A 99340
beta
Phosmidosine C 146425
Novel gonadotropin
MAC
RBP4 抗体 (YA100)（RBP4 Antibody (YA100)）
Histone H3 (21
Brain
1
CDC14A/B
Cdc19 amyloid core peptide
CDK1
Gc
SERT/NET
SM45a 2764770
(R)
Cusculine (FAC21)
Farrerol attenuates β
Acid
Tandospirone citrate 112457
Iron sucrose (Iron saccharate，蔗糖铁)
远上游元件结合蛋白 3（FUBP3）基因
α
Identification and determination of four metabolites of mangiferin in rat urine PMID 17723287
VX
AQP1 Deficiency Drives Phthalate
MCE
170575
4
Efficacy and mechanisms of concentrated growth factor on facial nerve rehabilitation in a rabbit model PMID 39831451
含 CKLF 样 MARVEL 跨膜结构域 3（CMTM3）基因
SB
Ultra
NSC12404 5411
Investigation of Anti
OMDM
A chemical tuned strategy to develop novel irreversible EGFR
NCR 631 160911
Sabestomig 2648346
蛋白激酶 AMP 激活的非催化亚基 γ 1（PRKAG1）基因
GGT
Synthesis and antiproliferative activity of monocationic arylthiophene derivatives PMID 27951487
Antibacterial and synergistic activity of isocryptomerin isolated from Selaginella tamariscina PMID 19307771
Selective and functional 5
ZG
Microbial
Ibezapolstat hydrochloride 1275582
Tofacitinib Prodrug
Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1 PMID 26443277
Antituberculosis Drug Interactions with Membranes A Biophysical Approach Applied to Bedaquiline PMID 31671599
Sitagliptin impurity 26
Neuronal CDK5RAP3 deficiency leads to encephalo
Targeting c
Dicamba
Structure
Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV
DL
Phellodendrine 6873
The anticholinergic drug oxybutynin inhibits voltage
HJC0197 1383539
ATX inhibitor 5 2402772
Synthesis, molecular modeling and biological evaluation of chalcone thiosemicarbazide derivatives as novel anticancer agents PMID 21816517
Sepofarsen (QR 110)
gamma
Mecamylamine hydrochloride 826
Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead structural analysis of binding mode to mature and zymogen
CRBN ligand
Arterolane maleate 959520
H7N9 influenza A virus activation of necroptosis in human monocytes links innate and adaptive immune responses PMID 31165725
Des
Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF) PMID 16364190
Design and selection of DMP 850 and DMP 851 the next generation of cyclic urea HIV protease inhibitors PMID 9831533
Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells PMID 32217690
Lumigen APS
GCA
(Rac)
Famotidine impurity 3 hydrochloride (Famotidine impurity C hydrochloride)
CDC25
CSN1S1 Human Pre
PPACK 71142
AMPK Regulates M1 Macrophage Polarization through the JAK2/STAT3 Signaling Pathway to Attenuate Airway Inflammation in Obesity
Rbm14 Mouse Pre
Astin B, a cyclic pentapeptide from Aster tataricus, induces apoptosis and autophagy in human hepatic L
MCE
Impaired mitochondrial integrity and compromised energy production underscore the mechanism underlying CoASY protein
Glioblastoma cell motility depends on enhanced oxidative stress coupled with mobilization of a sulfurtransferase PMID 36310164
Slow starch digestion in the rice cooked with adzuki bean Contribution of procyanidins and the oxidation products PMID 30884648
Cortistatin ameliorates Ang II
Kabiramides J and K, trisoxazole macrolides from the sponge Pachastrissa nux PMID 21410162
RP
NDI
SIRT3 attenuates sepsis
18 0 Lyso PS sodium (18 0 溶血剂 PS)
Ac4ManNDAz 1015698
(S)
Cholesterol efflux from C1QB
BODIPY
Matrine inhibits the proliferation of pituitary tumor cells by decreasing Foxo3a phosphorylation and promoting Foxo3a nuclear localization PMID 30988763
Alagebrium targets the miR
5'
t
YM598, an orally active ET(A) receptor antagonist, ameliorates the progression of cardiopulmonary changes and both
NOTCH2 蛋白, Human (HEK293, Fc)
(1R,3S)
5
Midkine promotes renal fibrosis by stabilizing C/EBPβ to facilitate endothelial
Diethylamine NONOate diethylammonium salt 372965
4'
Imaging of Tie2 with a Fluorescently Labeled Small Molecule Affinity Ligand PMID 31809013
Pharmacological study of broperamole, a chemical novel antiinflammatory compound PMID 6968217
Mesenchymal and stem
Astragalus polysaccharide regulates the cervical cancer cell cycle and inhibits cisplatin resistance by blocking the Wnt/β
Myristoleoyl
Deferiprone
SAR228810 an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid
Hypoxia Studies with Pimonidazole in vivo PMID 27453908
Pdk4 Rat Pre
Tridocosapentaenoin 370066
Inhibition of HMOX1 by MAFG potentiates the development of depression‑like behavior in mice associated with astrocyte
CRBN ligand
PRR20A Human Pre
PROCR Human Pre
NEU617 1432450
2(S)
Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac
L
K2004
Ferroptosis/apoptosis inducer
402117
WDHD1 蛋白, Human (HEK293, FLAG)
Chimeric antigen receptor
Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis PMID 31826695
β
Palmitoleoyl ethanolamide 94421
Design and synthesis of novel pyrazolo[1,5
2
N
钙/钙调蛋白依赖性蛋白激酶 II α（CAMK2A）基因
Trilaciclib 1374743
Chloro 2,3,4,6
DM1 Impurity 936481
Mechanistic insights into baicalein's anti
O,O
Pyroptosis mediated by Parkin
CL264 1510712
Synthesis, antitumor, cytotoxic and antioxidant evaluation of some new pyrazolotriazines attached to antipyrine moiety PMID 23022735
Simvastatin impurity 7
Tjp2
PRR4 Human Pre
PRR9 Human Pre
TJP2 Human Pre
Notch1 Rat Pre
The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin
CCR1 antagonist as a potential modulator of inflammatory, autophagic, and apoptotic markers in spinal cord injury PMID 39608704
Notoginsenoside R1 Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Apoptosis via Activating Wnt/β
Suppression of heparan sulfation re
HRH3 Human Pre
Tauromustine
[Clinical evaluation of a synthetic cough sedative guaiapate] PMID 367681
Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer PMID 39628575
Tnfsf4 Rat Pre
Penicillin V
4
NHSL2 Human Pre
PARP1/NAMPT
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