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PLGA
Rho kinase mediates transforming growth factor
Rotational Freedom, Steric Hindrance, and Protein Dynamics Explain BLU554 Selectivity for the Hinge Cysteine of FGFR4 PMID 31413803
Cyld Rat Pre
Cnn1 Rat Pre
Therapeutic effects of imidazolineoxyl N
C1qb
Photoinitiated polymerization of PEG
Nonafluoro
Recql4
Bst1 Rat Pre
Development of Small Molecules that Specifically Inhibit the D
Gnb2 Mouse Pre
L
Faziprumig (CLN
16alpha
Nitric oxide induces apoptosis and autophagy; autophagy down
Design, synthesis and evaluation of pyrrolobenzodiazepine (PBD)
A novel P38α MAPK activator Bruceine A exhibits potent anti
Hydroxyethyl starch (MW170
Donepezil promotes neurogenesis via Src signaling pathway in a rat model of chronic cerebral hypoperfusion PMID 32184165
ERα17p, an ERα P295
Glyctk Rat Pre
Development of Selective, Orally Active GPR4 Antagonists with Modulatory Effects on Nociception, Inflammation, and Angiogenesis PMID 28445047
Electrospray ionisation mass spectrometry (ESI
Blockade of IL
Celery extract 89997
ASK1
TRIM21
Azimilide (NE
Mechanism
Z
Betulinic acid derivative
羟酰谷胱甘肽水解酶（HAGH）基因
Alacepril 74258
6
Flumethrin (Standard) (FCR 2769 (Standard))
Rivastigmine impurity 3 (Rivastigmine impurity B)
Human Serum Albumin
DCTN1 Human Pre
PLLA1000
D
MCE
STK33 kinase inhibitor BRD
Factors influencing the conversion of carotenoids to retinol bioavailability to bioconversion to bioefficacy PMID 11887751
Development of 3
dioxide
SMND
GCG inhibits SARS
Anacardic Acids from Knema hookeriana as Modulators of Bcl
Progenitor effect in the spleen drives early recovery via universal hematopoietic cell inflation PMID 39864058
CCR1 antagonist 10 1010731
Lanostane Triterpenoids with Glucose
N
Preclinical antitumor activity of an alpha
兔单克隆抗体定制服务
Z
Safety, tolerability, and effect of food on the pharmacokinetics of iloperidone (HP 873), a potential atypical antipsychotic PMID 7560252
POPG sodium salt 268550
Toxic effects of environment
Dnase1l3 Rat Pre
The two mechanisms of action of racemic cardiotonic EMD 53998, calcium sensitization and phosphodiesterase inhibition, reside in different enantiomers PMID 7687712
Hcrt
SB
169841
Comparison of the acute toxicity, analgesic and anti
SB 714786 584555
GSK3839919A 2081127
The proton
IL18BP Human Pre
Protocatechuic acid
EP1 receptor antagonist
Incorporation of multiple sequential pseudothymidines by DNA polymerases and their impact on DNA duplex structure PMID 18260010
N
MCE
TQ
Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome B5 PMID 19022943
Withanoside IV and its active metabolite, sominone, attenuate Abeta(25
Fn1
Basroparib overcomes acquired resistance to MEK inhibitors by inhibiting Wnt
Maresin
Identification of a complete Cek7 receptor protein tyrosine kinase coding sequence and cDNAs of alternatively spliced transcripts PMID 7958948
Prostaglandin E1
Cldn8 Mouse Pre
Pyridoxal phosphate prevents progression of diabetic nephropathy PMID 17449494
Discovery of CYT997 a structurally novel orally active microtubule targeting agent PMID 19616947
A novel zebrafish jak2a(V581F) model shared features of human JAK2(V617F) polycythemia vera PMID 19772888
Miltirone Is a Dual Inhibitor of P
Bay
Folated synperonic
Preparation and in vitro biological evaluation of tetrapyrrole ethanolamide derivatives as potential anticancer agents PMID 17993275
Cyclopropanesulfonyl chloride 139631
FGFR
Circular RNA CREBBP modulates cartilage degradation by activating the Smad1/5 pathway through the TGFβ2/ALK1 axis PMID 36224344
CD40 pathway activation reveals dual function for macrophages in human endometrial cancer cell survival and invasion PMID 22903346
RANBP10 Human Pre
Design and synthesis of biaryloxazolidinone derivatives containing a rhodanine or thiohydantoin moiety as novel antibacterial agents against Gram
Gnb2 Rat Pre
Environmental factors influence goat immune response to PFOS and glyphosate Difference between grazing and stall
DR3/TNFRSF25 蛋白, Human (Biotinylated, HEK293, Fc)
Effect of pomiferin administration on kidney ischaemia
Difenoconazole
Discovery of novel small molecule cell type
FB102
T
Effects of a synthetic PEG
Pomalidomide
Discovery of selective nonpeptidergic neuropeptide FF2 receptor agonists PMID 19803524
DNA polymerase beta
Interleukin
Optimization of biaryloxazolidinone as promising antibacterial agents against antibiotic
L16726
Effect of AS2521780, a novel PKCθ selective inhibitor, on T cell
Tubulin polymerization
PD130883 123685
Production and biological activity of rebeccamycin, a novel antitumor agent PMID 3112080
hsa
ATM Inhibitor
[3,5 Diiodo
Ethnobotanical Uses, Phytochemistry, Toxicology, and Pharmacological Properties of Euphorbia neriifolia Linn. against Infectious Diseases A Comprehensive Review PMID 35889247
Diethylene glycol diacetate 628
Stibophen
Itacitinib adipate 1334302
Alternation in sequence features and their influence on the anti
2
PAI
BRD4 Inhibitor
Therapeutic antibody targeting of Notch1 in T
Novel Sulfonamide Derivatives as Anticancer Agents, VEGFR‑2 Inhibitors, and Apoptosis Triggers Design, Synthesis, and Computational Studies PMID 40949276
Influences of long
Laidlomycin phenylcarbamate
The protective effects of SA3443, a novel cyclic disulfide, on chronic liver injuries in rats PMID 1744424
TRV
Novel naphthalimide derivatives as potential apoptosis
Ehd1
Conversion of levoglucosan into glucose by the coordination of four enzymes through oxidation, elimination, hydration, and reduction PMID 33208778
S7 853248
Tumor necrosis factor α
(1S,2S)
LSP
Bisfentidine 96153
Fmoc
SHMT inhibition is effective and synergizes with methotrexate in T
JWJ
Benzyl
2'
SCR7 pyrazine 14892
Syntaxin
Thiophene E 64165
Discovery of a Highly Selective Cell
Antiproliferative and Anti
GRM1 modulator
Thevebioside, the active ingredient of traditional Chinese medicine, promotes ubiquitin
HPK1
(S)
NRF2 supports non
Resolvin D1 Inhibits IL
hsa
S100P Human Pre
VT103 2290608
Dimeric 3,5
DNA methylation
Human Serum Albumin
Selvigaltin 1978336
CAPRIN1 Human Pre
Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens PMID 31481610
Inhibition of Mcl
cyclin T2a/b 抗体 (YA9162)（cyclin T2a/b Antibody (YA9162)）
NOD1 activation promotes cell apoptosis in papillary thyroid cancer PMID 35430507
蛋白质二硫键异构酶家族 A 成员 4（PDIA4）基因
Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors PMID 28904064
Crocin exerts anti
Triterpenoids as novel natural inhibitors of human cathepsin L PMID 25238076
Antiangiogenic effect of TW37, a small
CASQ2 Human Pre
Antibody
Procr Rat Pre
Lactobacillus delivery of bioactive interleukin
Two Birds One Stone Strategy for the Site
B4galt5 Rat Pre
Visible Light Photoinitiator for 3D
Ccl3 Rat Pre
Effect of alpha
ABCB1
Blockade of Tim
Chamaejasmenin C 89595
Cytoglobin regulates NO
Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS
Fmoc
Il16 Mouse Pre
New Inhibitors of β
GALT Human Pre
AM404 183718
Zamicastat (Standard)
BMS
Hspa1b
Protein Ubiquitination Assay PMID 36180631
WNT3A Human Pre
Glyctk Mouse Pre
DZX19
β
Isoxazole compound ML327 blocks MYC expression and tumor formation in neuroblastoma PMID 29207623
Synthesis of [¹⁸F]
CD41 抗体 (YA3706)（CD41 Antibody (YA3706)）
20
Luisols A and B, new aromatic tetraols produced by an estuarine marine bacterium of the genus Streptomyces (Actinomycetales) PMID 10217720
DBCO
CSF1R
Transforming and tumorigenic activity of JAK2 by fusion to BCR molecular mechanisms of action of a novel BCR
Metabolic study of selective androgen receptor modulator LY2452473 in thoroughbred horses for doping control PMID 36758220
Effects of ketoconazole and rifampicin on the pharmacokinetics of GLS4, a novel anti
The estrogen receptor alpha
Discovery of a novel 6,7
Cd46
MMAI hydrochloride 132980
Mycotoxin F2
Vilazodone Intermediate
NRX
N
N
Vitisin A suppresses LPS
Oseltamivir 196618
TMRM Perchlorate 115532
STING immune activation of microglia aggravating neurovascular unit damage in diabetic retinopathy PMID 40158743
3
CP944629
Pigq Mouse Pre
Pregnenolone can protect the brain from cannabis intoxication PMID 24385629
PROTAC BCL6 Degrader
AT
(S)
Identification of LEM
Gut microbiota dysbiosis
Epiderstatin, a new inhibitor of the mitogenic activity induced by epidermal growth factor. I. Taxonomy, fermentation, isolation and characterization PMID 2584144
Hesperetin 5
Functional polarization of human hepatoma HepaRG cells in response to forskolin PMID 30382126
Schisantherin A protects against 6
Myt1
6
PCNP promotes ovarian cancer progression by accelerating β
(R)
Anti
Ginsenoside CK induces apoptosis in triple
Electrostatic adsorption of polyanions onto lipid nanoparticles controls uptake, trafficking, and transfection of RNA and DNA therapies PMID 38437543
Miltirone induces GSDME
LDLR 蛋白, Cynomolgus (HEK293, His)
A new natural naphtho[1,2
(Z
Design, Synthesis, and Bioactivity Evaluation of Dual
Phyllanthus niruri extract
CNS distribution, signalling properties and central effects of G
System analysis based on glutamine catabolic
Hepatitis B Virus Core Protein Is Not Required for Covalently Closed Circular DNA Transcriptional Regulation PMID 36226986
AZD
PNU‐142721 185220
A single injection of corifollitropin alfa supplemented with human chorionic gonadotropin increases follicular recruitment and transferable embryos in the rabbit PMID 30676677
Synthesis of natural 3'
曲妥单抗
Cwc15 Rat Pre
BODIPY TMR Lyso PE ester 2260795
Diclofenac impurity 8 (Diclofenac impurity B)
Bioactive dibenzocyclooctadiene lignans from the stems of Schisandra neglecta PMID 23738539
Quantitative determination of the anticancer prodrug combretastatin A1 phosphate (OXi4503, CA1P), the active CA1 and its glucuronide metabolites in human urine and of CA1 in plasma by HPLC with mass spectrometric detection PMID 22578514
Pharmacological studies on (4S)
TIM
Soyasaponins Aa and Ab exert an anti
IL
Plumbagin ameliorates LPS
Soyasaponin Ab ameliorates colitis by inhibiting the binding of lipopolysaccharide (LPS) to Toll
Hemidesmus indicus extract 90045
Anti
ICI 89406 53671
VPS35L Human Pre
Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists PMID 37391393
Anticancer effect of COX
IL
UCB
LAMP1/CD107a 蛋白, Mouse (HEK293, His)
HP1 gamma 抗体 (YA733)（HP1 gamma Antibody (YA733)）
Cottoquinazoline A and cotteslosins A and B, metabolites from an Australian marine
TG101209, a small molecule JAK2
Fgf19 Rat Pre
Mrps10
Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice PMID 29891873
ANKRD1
Momelotinib for the treatment of myelofibrosis with anemia PMID 35603634
B3galt5
Boc
Schisantherin A suppresses osteoclast formation and wear particle
New CCK2 agonists confirming the heterogeneity of CCK2 receptors characterisation of BBL454 PMID 15480577
Vtcn1 Mouse Pre
2,2′,3,4,5,5′
Autophagy attenuates particulate matter 2.5
5
Liposomal Silymarin
CC
(S)
Co
The voltage
Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine PMID 2372557
Binding of alpha
Separase, securin and Rad21 in neural cell growth PMID 17450531
Antitumor agent
Discovery of small
6
Salvianolic acid C promotes osteogenic differentiation of bone marrow mesenchymal stem cells in osteoporotic rats through activation of AMPK/SIRT1 pathway PMID 37318001
Rnf40 Rat Pre
Synthesis of novel 2
Latanoprost lactone diol
Synergistic Interactions of MmpL3 Inhibitors with Antitubercular Compounds In Vitro PMID 28115355
IL16 Human Pre
Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia PMID 22892116
Shh Rat Pre
Host
Dihydroartemisinin Targets the NFIC/FBN1 Cascade to Enhance Wound Healing in Chronic Skin Ulcer by Inhibiting Fibroblast Ferroptosis PMID 40358939
Human Serum Albumin
BMS 564929
Microglia are dispensable for developmental dendrite pruning of mitral cells in mice PMID 37890992
Piezo1 balances the osteogenic
Exploring the monocrotaline animal model for the study of pulmonary arterial hypertension A network approach PMID 26403584
N
2
Taltirelin 103300
Fadolmidine 189353
EGFRvIII
3
Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress
Fgf14 Rat Pre
Talastine hydrochloride 16188
Discovery of A
RD
Receptor
Discovery of RG7834 The First
What exactly does the PfK13 C580Y mutation in Plasmodium falciparum influence? PMID 37974285
IL
Serum Albumin/ALB 蛋白, Human (HEK293, His)
CLDN18
1
Thiodigalactoside 51555
NMDA receptor modulator 3 2758256
Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure PMID 21957197
6
Liposomal Quercetin
MCL1 凋亡调节因子，BCL2 家族成员（Mcl1）基因
NSD2 methylates AROS to promote SIRT1 activation and regulates fatty acid metabolism
An allosteric inhibitor of sirtuin 2 blocks hepatitis B virus covalently closed circular DNA establishment and its transcriptional activity PMID 38641024
C1qtnf1
Innovative Non
KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK
TACI 抗体 (YA3512)（TACI Antibody (YA3512)）
3
Tumour cell responses to new fibroblast growth factor receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance PMID 22869148
TIM
Structure
Antiviral activities of compounds from aerial parts of Salvia plebeia R. Br PMID 27647011
Design, synthesis, and evaluation of novel 3,6
Triterpenes from Poria cocos are revealed as potential retinoid X receptor selective agonists based on cell and in silico evidence PMID 31444840
Hspa1b
Forskolin
MCL1 inhibition targets Myeloid Derived Suppressors Cells, promotes antitumor immunity and enhances the efficacy of immune checkpoint blockade PMID 38459020
Novel pyrimidoazepine analogs as serotonin 5
MCE
RNA 传感器 RIG
Design, synthesis and structural development of nonsecosteroidal VDR ligands based on the C,C'
GNB2 Human Pre
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1
白细胞介素 12 受体亚基 β 1（IL12RB1）基因
Notch1 signaling in NOTCH1
Psmd1 Rat Pre
Discovery of Phenylpyrazole Derivatives as a New Class of Selective Inhibitors of MCL
CD8 positive T
Discovery of novel anti
Rps2 Rat Pre
Antiangiogenic properties of cafestol, a coffee diterpene, in human umbilical vein endothelial cells PMID 22525673
Carbonic anhydrase II, Human
Eicosapentaenoic acid
Long noncoding RNA GAS6
Leptin Modulates Ovarian Granulosa Cell Apoptosis by Regulating Telomerase Activity and Telomere Length in Polycystic Ovary Syndrome PMID 39491652
Androgen receptor antagonist 9
Monitoring of selective androgen receptor modulators in bovine muscle tissue by ultra
Morfamquat (dichloride) 4636
Antifouling activity of macroalgal extracts on Fragilaria pinnata (Bacillariophyceae) a comparison with Diuron PMID 19726092
N
hCA/VEGFR
thrombocytes
(1H
ZIP9 mediates the effects of DHT on learning, memory and hippocampal synaptic plasticity of male Tfm and APP/PS1 mice PMID 37305050
BACE
Fmoc
beta
Dihydroevocarpine 15266
2
RPR
Anti
Functionalized magnetic
Ramipril impurity 4 (Ramipril impurity O)
Anti
Transplantation of miR
M&B 5124 15382
Benzothiazepine CGP37157 Analogues Exert Cytoprotection in Various in Vitro Models of Neurodegeneration PMID 26192029
SIRT4 Suppresses Doxorubicin
VX
valine
DNASE1
Hexyl
Quercetin 5
N
Herpes simplex virus
Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine
Daturabietatriene 65894
Tolterodine 124937
Exploring the impact of RPN1 on tumorigenesis and immune response in cancer PMID 40079196
Phospho
Effects of Nrf
CCG
Fanapanel hydrate 1255517
Bisphenol A
Discovery of a Novel Serine
Discovery of Novel Quinazolinone
CC chemokine receptor 2 is allosterically modulated by sodium ions and amiloride derivatives through a distinct sodium ion binding site PMID 39111604
GSK8470 1276664
Fasitibant free base 869939
Important role of interleukin
Anti
Toxicokinetics of T
NBD
LncRNA HANR promotes the aerobic glycolysis in prostate cancer by stabilizing TPI1 PMID 40921293
Discovery of Mcl
Alad Rat Pre
Ethylmalonic acid induces permeability transition in isolated brain mitochondria PMID 24557940
己基β
PRODAN
辛伐他汀EP杂质C (Anhydro Simvastatin) (Standard)
147657
Discovery of XL01126 A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood
CRBN ligand
Blockade of ENaCs by amiloride induces c
Erythrinaline alkaloids from the flowers and pods of Erythrina lysistemon and their DPPH radical scavenging properties PMID 15231413
Design, Synthesis, and Biological Evaluation of 3
Ethyl 5
orthophosphate monoester
CYT997 a novel orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo PMID 19887548
Tirotundin 56377
The Role of Endothelial Barrier Function in the Fibrosis of Salivary Gland PMID 36112881
The sulfonadyns a class of aryl sulfonamides inhibiting dynamin I GTPase and clathrin mediated endocytosis are anti
Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti
Synthesis and antiproliferative activity of helonioside A, 3',4',6'
kaempferol
Sirukumab for the treatment of rheumatoid arthritis update on sirukumab, 2018 PMID 29925278
GLIPR2 Human Pre
Fmoc
DBCO
N
neurohormone
Ube2g1
Synthesis and structure
Bruceine A Suppressing metastasis via MEK/ERK pathway and invoking mitochondrial apoptosis in triple
Circadian gene PER1 senses progesterone signal during human endometrial decidualization PMID 31518992
Macrocyclic Carbon
(Rac)
Identification of new selective CD36 inhibitors to potentiate HER2
FCGRT Human Pre
Escitalopram impurity 5 (Escitalopram impurity F)
Promiscuous G
Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2
Donepezil impurity 9 (Donepezil impurity G)
SHTN1 Human Pre
Cholesterol biosynthesis inhibitor RO 48‑8071 inhibits pancreatic ductal adenocarcinoma cell viability by deactivating the JNK and ERK/MAPK signaling pathway PMID 34590153
Human Serum Albumin
NMDA receptor antagonist 2 875898
Patient
IL21R Human Pre
Salbutamol impurity 2 (Salbutamol impurity J)
Prmt2 Rat Pre
Response of Arabidopsis thaliana to N
Nonivamide enhances miRNA let
AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c
Il18 Mouse Pre
Preclinical characterization of GLS4, an inhibitor of hepatitis B virus core particle assembly PMID 23959305
Tnfsf4
Decyl 1
Toxicity and photosensitizing assessment of gelatin methacryloyl
β
Structure
Sae1
Protective effect of α7 nicotinic acetylcholine receptor activation on experimental colitis and its mechanism PMID 36058917
Design, synthesis, and bioactivity evaluation of macrocyclic benzo[b]pyrido[4,3
Discovery of small molecule inhibitors of MyD88
A peptide inhibitor of macrophage migration in atherosclerosis purified from the leech Whitmania pigra PMID 32119950
肺动脉高压是肺动脉高压
N',2
Umbilical Cord
Berberine modulates ASK1 signaling mediated through TLR4/TRAF2 via upregulation of miR
Targeting Oncogenic Mutant p53 for Cancer Therapy PMID 26732534
end
(S)
Modulating the Binding Kinetics of Bruton's Tyrosine Kinase Inhibitors through Transition
The immunosuppressive potency in vitro of physiological and synthetic steroids on lymphocyte cultures PMID 3497887
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