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Izencitinib 2051918
Epimerization and racemization of some chiral drugs in the presence of human serum albumin PMID 2337941
Design, synthesis and characterization of aryl bis
H
BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency PMID 31769494
Fullerene C60 Penetration into Leukemic Cells and Its Photoinduced Cytotoxic Effects PMID 28091953
Design, synthesis, and structure
Odor compound detection in male euglossine bees PMID 12647866
TSG101 抗体 (YA025)(PBS only)（TSG101 Antibody (YA025)(PBS only)）
Lgals4 Mouse Pre
Synthesis and β
A polycistronic system for multiplexed and precalibrated expression of multigene pathways in fungi PMID 37460548
Casuarictin A new herbal drug molecule for Alzheimer's disease as inhibitor of presenilin stabilization factor like protein PMID 33294689
Suberosin 581
Photocrosslinking
ATP
Generation and characterization of a humanized anti
Regulating Neutrophil PAD4/NOX
A Fluorescence Dequenching
AZD
Emmolic acid, acetate (乙酸茶酸酯)
(R)
Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging PMID 37277641
Exploring bi
Generation and Characterization of Mirikizumab, a Humanized Monoclonal Antibody Targeting the p19 Subunit of IL
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain PMID 19734051
Integrating transcriptomics and network pharmacology to reveal the mechanisms of total Rhizoma Coptidis alkaloids against nonalcoholic steatohepatitis PMID 38103844
Cinaciguat in combination with insulin induces a favorable effect on implant osseointegration in type 2 diabetic rats PMID 31319371
Il16
Actinomycin D and 7
Anle138b
Tucidinostat 1616493
Lactimidomycin is a broad
Design and Synthesis of Pyridone
HY
ASP
1
7711
An NTCP
Skp2
Tumor cell death mediated by peptides that recognize branched intermediates of DNA replication and repair PMID 24244353
INCENP 抗体 (YA6960)(PBS only)（INCENP Antibody (YA6960)(PBS only)）
8Br
Side
beta
In vitro pharmacology of aripiprazole, its metabolite and experimental dopamine partial agonists at human dopamine D2 and D3 receptors PMID 21816144
CCNDBP1 Human Pre
Ru(II)
Heterodimeric GW7604 Derivatives Modification of the Pharmacological Profile by Additional Interactions at the Coactivator Binding Site PMID 33904307
A CD4 mimic as an HIV entry inhibitor pharmacokinetics PMID 24189188
Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate PMID 8641665
N
VPC285785
Fmoc
Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's Disease PMID 28929759
A
FXR protects against neonatal sepsis by enhancing the immunosuppressive function of MDSCs PMID 40335739
L
Anti
Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ
Obeticholic acid attenuates the intestinal barrier disruption in a rat model of short bowel syndrome PMID 38718845
Design and Discovery of New Dual Carbonic Anhydrase IX and VEGFR
15
Discovery of a Potent and Highly Selective Inhibitor of Aurora A Kinase PMID 41089486
Antimycobacterial agent
Florensocatib 2762114
The lichen secondary metabolite atranorin suppresses lung cancer cell motility and tumorigenesis PMID 28811522
Design and synthesis of novel orally selective and type II pan
(R)
The combination of CHK1 inhibitor with G
TACI
Hexb Rat Pre
The cytotoxic and tyrosine kinase inhibitory properties of C21 steroids and iridoids from the tubers of Alocasia cucullata PMID 27120176
Ursolic acid targets secreted phosphoprotein 1 to regulate Th17 cells against non
(S)
Evidence for a sustained effectiveness of sodium
Enhanced gene expression by a novel stearylated INF7 peptide derivative through fusion independent endosomal escape PMID 19465073
Inhibition of platelet aggregation and reversal of vasopressin
EGFR
Identification of Novel Bisamide
In vitro and in vivo evaluations of oxacillin efficiency against mecA
Triazole
ERK5 and Cell Proliferation Nuclear Localization Is What Matters PMID 27713878
Small
Ddb1
Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum PMID 27405106
Nifurpipone, a new nitrofuran with a large antimicrobial spectrum PMID 5001825
2'
MCE
Discovery of New N
Phospho
Senkyunolide A 63038
MMP
Sodium lauryl sulfate increases the efficacy of a topical formulation of foscarnet against herpes simplex virus type 1 cutaneous lesions in mice PMID 10952566
Design and synthesis of novel tricyclic benzoxazines as potent 5
Delphinidin
Versatility of subtilisin A review on structure, characteristics, and applications PMID 35019178
Inhibitors of bacterial transcription initiation complex formation PMID 23751807
Targeting the DENV NS2B
Intestinal neutrophil extracellular traps promote gut barrier damage exacerbating endotoxaemia, systemic inflammation and progression of diabetic retinopathy in type 2 diabetes PMID 39875729
PLOD1 promote proliferation and migration with glycolysis via the Wnt/β
Dual effects of isoflavonoids from Pueraria lobata roots on estrogenic activity and anti
Induction of cytokinin autonomy by N,N'
Cesium
CM03 2101208
Glycyl H
RJG
Cisatracurium myographical and electrophysiological studies in the isolated rat muscle PMID 16671964
CDK7
Detection of vascular adhesion molecule
Effects of 2',6'
Spinacetin Suppresses the Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mouse Model PMID 30104977
Bisindenoisoquinoline bis
Anti
1
Epibestatin hydrochloride
Deficiency of 3
TADA3 Human Pre
Nacubactam Enhances Meropenem Activity against Carbapenem
Platelets induce CD39 expression in tumor cells to facilitate tumor metastasis PMID 38461171
Technical Support
Effects of thiazinamium chloride and other antihistamines on phosphatidylcholine secretion in rat type II pneumocyte cultures PMID 2880592
Aminoacetone hydrochloride 7737
Antiprotozoal activity and DNA binding of N
GSK046 2474876
A new sweet dihydrochalcone
Discovery of a novel homoisoflavonoid derivative 5g for anti
Calceolarioside B 105471
EA
17
Inhibition Mechanism and Target Reassessment of Potent Piperaquine Analogs Evidence for Pf LDH over Pf DHODH PMID 41427238
Pharmacological profile of JNJ
Design, synthesis and biological evaluation of naphthostyril derivatives as novel protein kinase FGFR1 inhibitors PMID 24939105
IL19 Human Pre
A near
Chloro
Chemistry of renieramycins. Part 3.(1) isolation and structure of stabilized renieramycin type derivatives possessing antitumor activity from Thai sponge Xestospongia species, pretreated with potassium cyanide PMID 14640515
Design, synthesis and evaluation of novel oxazaphosphorine prodrugs of 9
S1P1 agonist 1 (Standard)
Development of a Potent and Selective G2A (GPR132) Agonist PMID 38917049
B2M/Beta
Ogdh
Discovery of 3
Amisometradine 550
Blood pressure reduction in hypertensive
Discovery of a Myeloid Cell Leukemia 1 (Mcl
Pectin A Long
IMM
A Multicenter, Randomized, Double
DNASE1L2 Human Pre
A tetramethyl rhodamine (Tamra) phosphoramidite facilitates solid
Antinociceptive effect of tebanicline for various noxious stimuli
VCAN Human Pre
Chromatin immunoprecipitation (ChIP) for analysis of histone modifications and chromatin
Antitorsadogenic effects of ({+/
The development of potent, competitive CXCR4 antagonists for the prevention of cancer metastasis PMID 37956893
Rosiglitazone
Design, synthesis and biological evaluation of novel 2,3,4,9
Chemoproteomics
Combined treatment with dihydrotestosterone and lipopolysaccharide modulates prostate homeostasis by upregulating TNF
Carbohydrate sulfotransferases a review of emerging diagnostic and prognostic applications PMID 37545696
MMP2
Lanostane Triterpenes Isolated from Antrodia heteromorpha and Their Inhibitory Effects on RANKL
Molecular specificity of 5
Antagonist effects of seglitide (MK 678) at somatostatin receptors in guinea
Vazegepant hydrochloride (Zavegepant (hydrochloride))
Il22 Rat Pre
Protective effect of indole
Discovery of potent hypoxia
DNASE1 Human Pre
Rapid generation of incremental truncation libraries for protein engineering using alpha
Catalytic Inhibition of p300 Preferentially Targets IRF4 Oncogenic Activity and Tumor Growth in Multiple Myeloma PMID 41248492
Preclinical Evaluation of a Companion Diagnostic Radiopharmaceutical, [18F]PSMA
Platelet
Adefovir dipivoxil PMID 10493275
Rhodium
RPS26 Human Pre
2
Rac1 Inhibitor F56, control peptide 1315378
4
gamma
ACSL4 upregulates IFI44 and IFI44L expression and promotes the proliferation and invasiveness of head and neck squamous cell carcinoma cells PMID 38989827
Acute, mutagenicity, teratogenicity and subchronic oral toxicity studies of diaveridine in rodents PMID 26397222
N1
Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite PMID 16272121
Ziprasidone
Model system for irreversible inhibition of Nek2 thiol addition to ethynylpurines and related substituted heterocycles PMID 24213855
Anti
Additive cardiotoxicity of a bisphenol mixture in zebrafish embryos The involvement of calcium channel and pump PMID 37418940
Tafuramycin A 494868
(S)
IL17RC Human Pre
Intrapeptide regulation of protein kinase C PMID 8132562
c17orf74 抗体 (YA6844)（c17orf74 Antibody (YA6844)）
Identification of distinct endoglycosidase (endo) activities in Flavobacterium meningosepticum endo F1, endo F2, and endo F3. Endo F1 and endo H hydrolyze only high mannose and hybrid glycans PMID 1899092
TAK
CENPC 抗体 (YA2227)（CENPC Antibody (YA2227)）
MCE
HLCL
Estrogen receptor β mediates the feedback loop between 17β
Potent HIV‑1 protease inhibitors containing oxabicyclo octanol
PF
(E)
MCE
DDX6 抗体 (YA2252)（DDX6 Antibody (YA2252)）
(R)
C5a receptor targeting in neointima formation after arterial injury in atherosclerosis
Characterization of JNJ
Etalanetug 2690265
Rhynchophylline suppresses soluble Aβ1
Anti
Structure
DAPM 208255
Degarelix, a novel GnRH antagonist, causes minimal histamine release compared with cetrorelix, abarelix and ganirelix in an ex vivo model of human skin samples PMID 20840449
hsa
BI
Danvilostomig 2599198
Protective effect of procyanidin A
Probing the presence of the ligand
MCE
A clinical study to assess CYP1A2 and CYP3A4 induction by AZD7325, a selective GABA(A) receptor modulator
2
NBI
tert
Inhibition of 3
ZFP42 抗体 (YA4433)(PBS only)（ZFP42 Antibody (YA4433)(PBS only)）
Prostaglandin E Synthase 抗体 (YA1741)(PBS only)（Prostaglandin E Synthase Antibody (YA1741)(PBS only)）
Mumefural Improves Blood Flow in a Rat Model of FeCl3
2
Parathion
Cardiovascular and pharmacological implications of haem
Somatostatin inhibition of gonadotropin
7,4'
SCH 40120 110545
Merging PROTAC and molecular glue for degrading BTK and GSPT1 proteins concurrently PMID 34417569
TOX2 Human Pre
Cinoxacin
RA190 1617495
Crovozalpon 2406205
Recombinant OX40 attenuates neuronal apoptosis through OX40
Identification of the Metabolic Profile of the α
Diagnostic value of microtubule
Cd99 Rat Pre
Crosstalk Among NLRP3 Inflammasome, ETBR Signaling, and miRNAs in Stress
Synthesis of a novel biotin
N
Fatty acid profiles in demented patients identification of hexacosanoic acid (C26 0) as a blood lipid biomarker of dementia PMID 25428249
Reversal of morphine tolerance by a compound with NPFF receptor subtype
Physiologic effect of repeated adrenaline (epinephrine) doses during cardiopulmonary resuscitation in the cath lab setting A randomised porcine study PMID 26876006
Novel dipeptidyl proteasome inhibitors overcome Bcl
Pamapimod
Dansylglycine 1091
Rev‑erbα The circadian guardian against NLRP3‑driven liver fibrosis PMID 40709400
Cefpodoxime proxetil EP impurity A
Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet
PTEN inhibits epithelial mesenchymal transition of thyroid cancer cells by regulating the Wnt/β
Monoclonal antibodies to fibroblast growth factor receptor 2 effectively inhibit growth of gastric tumor xenografts PMID 20670946
Ephrin
(+)
Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma PMID 28118603
Flavonoids and 3
Untargeted metabolomics confirms and extends the understanding of the impact of aminoimidazole carboxamide ribotide (AICAR) in the metabolic network of Salmonella enterica PMID 29417056
Rb1 Rat Pre
Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice PMID 25941626
HDAC6 deacetylates IDH1 to promote the homeostasis of hematopoietic stem and progenitor cells PMID 37642636
M3 mAChR agonist 1 1624297
TORC2 抗体 (YA4325)（TORC2 Antibody (YA4325)）
CAP2 抗体 (YA568)(PBS only)（CAP2 Antibody (YA568)(PBS only)）
Chac1 Mouse Pre
Neotame 165450
way
TCF3 / E2A 抗体 (YA3815)（TCF3 / E2A Antibody (YA3815)）
Discovery of novel diarypyrimidine derivatives as potent HIV
A potent and selective TNKS2 inhibitor for tumor
Thyroid receptor ligands. 6. A high affinity direct antagonist selective for the thyroid hormone receptor PMID 17154490
Il17b
Discovery of Thermal Sensitizers That Inhibit Heat
Efficacy of volatile compounds from Streptomyces philanthi RL
Sesquiterpenes with TRAIL
Tissue factor signal transduction in angiogenesis PMID 12807741
Thymic Stromal Lymphopoietin (TSLP), Its Isoforms and the Interplay with the Epithelium in Allergy and Asthma PMID 37628907
Vitamin D Binding Protein 抗体 (YA009)（Vitamin D Binding Protein Antibody (YA009)）
Carboxyatractyloside (CATR)
RAB5A Human Pre
Properties of ligninase from Phanerochaete chrysosporium and their possible applications PMID 3322681
NU5455 1257235
Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412 PMID 25395427
Natural and synthetic flavonoid modulation of TRPC5 channels PMID 26565375
Phenazoviridin, a novel free radical scavenger from Streptomyces sp. Taxonomy, fermentation, isolation, structure elucidation and biological properties PMID 8244877
Estramustine phosphate induces prostate cancer cell line PC3 apoptosis by down
Production of novel antioxidative prenyl naphthalen
LY320135 176977
MeAIB 2566
Bimiralisib 1225037
Galectin
Small molecule
SHP844 2222280
hsa
Hydroxy carisoprodol
HY
Rabdosiin 263397
N
Fmoc
Halogenated trimethoprim derivatives as multidrug
5
In vivo Igkc Mouse Pre
Increasing the levels of insulin
Towards next
Studies on the metabolism of thymine and 6
MRT 68601 1190379
AV5116 2417851
Structure
Nonadecane 629
KU
(S)
CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response PMID 30323222
Carotenoids in marine invertebrates living along the Kuroshio current coast PMID 21892355
Mexiletine PMID 3537793
Site
SiR
Cholesterol
EGFR
Inhibition of excessive mitophagy by N
KRAS inhibitor
3β
OGT
Mitochondrial biogenesis in developing astrocytes regulates astrocyte maturation and synapse formation PMID 33852851
RO5454948 1386979
Redox properties and cytoprotective actions of atranorin, a lichen secondary metabolite PMID 21111802
BMS 564929
C527 192718
S
FR104
THE TREATMENT OF MENTAL SYMPTOMS IN THE AGED WITH PROTHIPENDYL (TOLNATE) PMID 14199907
Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice PMID 24599971
Antiprotozoal activity of bicyclic diamines with a N
Axl
Discovery of a ubiquitin
Transforming Growth Factor
Serotonergic receptor antagonist from Nandina domestica Thunberg PMID 6726648
PTEN 抗体 (YA119)(PBS only)（PTEN Antibody (YA119)(PBS only)）
4,4',4",4"',4"",4""'
3
Protective effects of the Bupi Yishen formula on renal fibrosis through PI3K/AKT signaling inhibition PMID 35367329
MCE
L
KIAA1199 promotes invasion and migration in non
Chemical cross
DCC 3014
GR 103691 (Standard)
6''
5
ADRM1 as a therapeutic target in hepatocellular carcinoma PMID 32916039
HTLA
2
CHIR258
trans
Theralizumab
Bicalutamide
androgen
Dact1
双特异性酪氨酸磷酸化调节激酶1A（Dyrk1a）基因
Aldosterone antagonist
Mechanism of Molecular Activity of Yolkin
pitressin
LY
Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors PMID 22615395
Anlotinib Overcomes Multiple Drug Resistant Colorectal Cancer Cells via Inactivating PI3K/AKT Pathway PMID 33438566
Boc
Two new coumarins from Herpetospermum caudigerum PMID 18239307
PIK
Diazoxide Attenuates Postresuscitation Brain Injury in a Rat Model of Asphyxial Cardiac Arrest by Opening Mitochondrial ATP
CHO
SC9420
Escin Ie 1613506
P4HA2 contributes to head and neck squamous cell carcinoma progression and EMT through PI3K/AKT signaling pathway PMID 38777998
DCC3014
TAB08
Discovery of (3S,3aR)
OPM2
Podocytes
Gi
carboxylic
Isogarcinol Reduces MARS Levels and Deactivates the PI3K/AKT Pathway to Suppress the Malignant Properties of Breast Cancer Cells PMID 40120049
Targeting KDM4C Prevents Heart Failure after Acute Myocardial Infarction Via Activation of SOS2 PMID 39900886
Torin 2 1223001
Nintedanib
Mineralocorticoid Receptor
Isoquinolin
DOTA
Biosynthesis of aphid alarm pheromone is modulated in response to starvation stress under regulation by the insulin, glycolysis and isoprenoid pathways PMID 33242454
Paracetamol (acetaminophen) warfarin interaction NAPQI, the toxic metabolite of paracetamol, is an inhibitor of enzymes in the vitamin K cycle PMID 15467911
A First
Rational Design of Resveratrol O
F 992
Inhibition of PHLPP1 ameliorates cardiac dysfunction via activation of the PI3K/Akt/mTOR signalling pathway in diabetic cardiomyopathy PMID 32150791
Enhanced UHPLC
BMS
Nephropathy
KMS11
Prolactin upregulates amino acids uptake in dairy cow mammary epithelial cells via LAT1 PMID 38945262
Nintedanib esylate 656247
Allylglycine intranigral effects and reappraisal of actions on the GABA system PMID 426864
pancreatic
Apicoplast biogenesis mediated by ATG8 requires the ATG12
EMPO 61856
Discovery and structure
Protein Serine
Vasopressin Receptor
Vat Black 27
Ferroptosis Induces gut microbiota and metabolic dysbiosis in Collagen
Sr
Dovitinib
Anti
(E)
(E)
A Novel Polysaccharide from the Flowers of Lilium lancifolium Alleviates Pulmonary Fibrosis In Vivo and In Vitro PMID 40114341
Acute Exposure of Veterinary Antibiotic Tilmicosin Leads to Idiopathic Scoliosis
castration
regulatory T cell
1,8
Bruceantinol
Ataxia telangiectasia mutated
Liraglutide Accelerates Ischemia
CaSR
Berberine Suppresses EMT in Liver and Gastric Carcinoma Cells through Combination with TGF β R Regulating TGF
TGN 1412
TAB08
anti
Esculentoside A inhibits tumor necrosis factor, interleukin
SC 9420
Algestone acetophenide 24356
Pharmacokinetics and antidiuretic effect of a new vasopressin analogue (F992) in overhydrated male volunteers PMID 10424322
Kinsenoside mitigates myocardial ischemia/reperfusion
Torin 2
Hypertensive effect of calcilytic NPS 2143 administration in rats PMID 17065402
Amino derivatives of indole as potent inhibitors of isoprenylcysteine carboxyl methyltransferase PMID 20809634
Kcnj2 Mouse Pre
Fmoc
Programmed death
PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway PMID 34718369
UNC9994
HIV
STT3B Human Pre
JNJ
D2R/β
near
Vascular and soft tissue calcification
Discovery of β
Melatonin receptor agonists SAR and applications to the treatment of sleep
USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway PMID 38531846
Effect of Nintedanib Nanothermoreversible Hydrogel on Neovascularization in an Ocular Alkali Burn Rat Model PMID 36259508
HIV
Manipulation of Surface Potential Distribution Enhances Osteogenesis by Promoting Pro
Interplay of multiple interaction forces Binding of tyrosine kinase inhibitor nintedanib with human serum albumin PMID 26894847
High Iodine Induces the Proliferation of Papillary and Anaplastic Thyroid Cancer Cells via AKT/Wee1/CDK1 Axis PMID 33796458
spirostanol saponin
PIK75
An evaluation of vimseltinib for treatment of tenosynovial giant cell tumors PMID 40014878
GCNT3 Promotes Hepatocellular Carcinoma Progression and EMT by Activating the PI3K/AKT Pathway PMID 38789846
JNJ
Drug Isomer
Porcine Acellular Dermal Matrix Promotes Migration and Suppresses Inflammation of Keratinocytes by Mediating the AKT Signaling Pathway PMID 38044138
Prenatal Lipopolysaccharides Exposure Induces Transgenerational Inheritance of Hypertension PMID 36004643
Two sex pheromone receptors for sexual communication in the American cockroach PMID 38523236
BIBF 1120
Pyrroloquinoline quinine protects HK
Emicizumab 1610943
JNJ 4929821
2
Immune monitoring
Rac1 signalling coordinates epiboly movement by differential regulation of actin cytoskeleton in zebrafish PMID 28668387
Involvement of the calcium
Nintedanib Inhibits Endothelial Mesenchymal Transition in Bleomycin
UNC
Pirfenidone and nintedanib attenuates pulmonary artery endothelial and smooth muscle cells transformations induced by IL
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer PMID 32406319
(3R,5S)
β
SC
Algestone acetophenide (Standard)
Puerarin attenuates intracerebral hemorrhage
LY294002 154447
多韦替尼
The PI3K
colorectal adenocarcinoma
Annexin A5 knockdown inhibits cardiomyocyte apoptosis and alleviates cardiac hypertrophy via activating the PI3K/AKT/Bcl
Ser/Thr Kinase
Astragaloside Ⅳ improves neuroinflammation in Parkinson's disease by regulating amino acid metabolism and the PI3K
PH
Characterization of SPK 98, a Torin2 analog, as ATR and mTOR dual kinase inhibitor PMID 32911078
Dexmedetomidine mitigates oxidative stress in H9C2 cardiac myoblasts under a high‑glucose environment via the PI3K/AKT signaling pathway PMID 40641117
AZD
Inhibition of Phosphatidylinositol 3
antipsychotic
Effect of a novel oral chemotherapeutic agent containing a combination of trifluridine, tipiracil and the novel triple angiokinase inhibitor nintedanib, on human colorectal cancer xenografts PMID 27805254
Ligustrazine protects against chronic hypertensive glaucoma in rats by inhibiting autophagy via the PI3K
Airway Epithelium
Traf2
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