最近收录_第936页_生物活性分子
生物活性分子最近更新
Benzodeazaoxaflavin Sirtuin Inhibitors Inhibit Schistosoma mansoni Sirt2 and Cause Phenotypic Changes and Lethality in Schistosomula and Adult Worm Stages PMID 41056475
排序 nexin 19（SNX19）基因
Cinoxacin 28657
Antitumor agent
Comparative local anesthetic potencies of lidocaine and metabutoxycaine PMID 13549177
肌球蛋白轻链 12A（MYL12A）基因
L
SCG3/Secretogranin
Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice PMID 18483626
Species
(±)
Mia2
ACVR1 抗体 (YA4179)（ACVR1 Antibody (YA4179)）
Propargyl
H
Pomalidomide 5'
Vindesine 53643
MCE
Fmoc
丝氨酸/精氨酸重复矩阵 4（SRRM4）基因
Stromal cell
Stromal cell
MCE
Chlorogenic Acid Alleviates Chronic Stress
Mer/c
<i>Streptomyces kitasatoensis</i>
INH6 1001753
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints PMID 15189136
COTI
乳酸钠
Caldesmon 抗体 (YA5721)（Caldesmon Antibody (YA5721)）
CRTH2
Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer's disease PMID 36368316
1,8
JNK1+JNK2+JNK3 抗体 (YA328)（JNK1+JNK2+JNK3 Antibody (YA328)）
Arizonins, a new complex of antibiotics related to kalafungin. I. Taxonomy of the producing culture, fermentation and biological activity PMID 3182401
Synthesis and Preclinical Evaluation of Novel 99mTc
Application of exogenous ceramide to cultured rat spinal motoneurons promotes survival or death by regulation of apoptosis depending on its concentrations PMID 9822158
Glutaminase
Isourolithin A 174023
Arg12 105151
Nobiletin alleviates atherosclerosis by inhibiting lipid uptake via the PPARG/CD36 pathway PMID 38468335
1
Br
2
α
Molecular cloning and pharmacological characterisation of a tyramine receptor from the rice stem borer, Chilo suppressalis (Walker) PMID 23129510
Ferrostatin
MCE
CTX1 501935
Gpx8
m
Calceolarioside B inhibits SARS
(S)
Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody
SPHKAP Human Pre
N
Microglial SIRT1 activation attenuates synapse loss in retinal inner plexiform layer via mTORC1 inhibition PMID 37670386
GSK484 1652629
CP
Sinulatumolin C 2570255
Differentiation of Hdm2
N
Top/HDAC
H
PHT
Pexidartinib Inhibits Macrophage Senescence Through Glycolysis in Periodontitis Microenvironment PMID 40460514
NUP88 Human Pre
MCE
ML221 (Standard)
h5
Discovery of a novel tricyclic 4H
DL
MCE
Rova
A rapid one
Inhibition of the bacterial heme oxygenases from Pseudomonas aeruginosa and Neisseria meningitidis novel antimicrobial targets PMID 17629261
diagnose
PAF1 抗体 (YA2505)（PAF1 Antibody (YA2505)）
NFQ1 1262391
PAβN dihydrochloride 100929
NPE
Bryonolic acid 24480
Gins1 Rat Pre
Enhancer RNAs Mediate Estrogen
Irtemazole (R 60844)
1,2
Hydrophobic drug delivery by self
INHBC Human Pre
PNGase F (MS grade)
ANGPT4 Human Pre
(S)
Resorufin
PAD4 inhibition impacts immune responses in SARS
PLGA
ROS1 抗体 (YA6747)（ROS1 Antibody (YA6747)）
Rhod Rat Pre
LP99 1808951
Growing a whole porcine liver organ ex situ for six hours without red blood cells or hemoglobin PMID 27398140
2
Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes PMID 32617965
Enriched environment ameliorates fear memory impairments induced by sleep deprivation via inhibiting PIEZO1/calpain/autophagy signaling pathway in the basal forebrain PMID 37485782
CVT
A
Clusterin alpha Chain 抗体 (YA2525)（Clusterin alpha Chain Antibody (YA2525)）
2
H
Inhibition of Toxoplasma gondii Growth by Dihydroquinine and Its Mechanisms of Action PMID 35646733
Endorphins and pain PMID 6316302
小核核糖核蛋白多肽 E（SNRPE）基因
Individual and combined antagonism of aryl hydrocarbon receptor (AhR) and estrogen receptors (ERs) offers distinct level of protection against Bisphenol A (BPA)
Cilofexor 1418274
Guanoxani sulfate 5714
MCE
HY
Discovery of Novel Inhibitors of the Tautomerase Activity of Macrophage Migration Inhibitory Factor (MIF) PMID 26933127
PLK1
细胞分裂周期 26（CDC26）基因
Grazoprevir impurity 1 1206524
Human Papilloma Virus
KJ Pyr 9 581073
Tos
CLEC4E
Tiprotimod 105523
Lys
Opposing roles of pseudokinases NRBP1 and NRBP2 in regulating L1 retrotransposition PMID 40645931
PKItide 126370
Anetumab ravtansine 1375258
Romifidine 65896
Biotin
Oxa
CBP/p300 ligand 10
Mettl3‑mediated m6A RNA methylation regulates osteolysis induced by titanium particles PMID 38214327
Detection of Dietary Chalcone and Flavonoid Metabolites in Mice Using UPLC
N
2,4
BMS
Sotatercept for the Treatment of Pulmonary Arterial Hypertension PMID 33789009
Molecular modeling and in vitro approaches towards cholinesterase inhibitory effect of some natural xanthohumol, naringenin, and acyl phloroglucinol derivatives PMID 29655693
(R)
Phospholipase C beta 3 抗体 (YA2694)（Phospholipase C beta 3 Antibody (YA2694)）
TEF Human Pre
脱帽酶，清除因子（DCPS）基因
CRBN ligand
PTP IA
C19ORF80 抗体 (YA7918)（C19ORF80 Antibody (YA7918)）
Lamb2 Mouse Pre
核糖体蛋白 L28（RPL28）基因
CW
((4'
2
(±)9(10)
In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil PMID 10906729
BRD4 Inhibitor
MCE
(4
Pharmacological profile of the thyroid hormone receptor antagonist NH3 in rats PMID 17440037
S100a11
Ucp1 Ablation Improves Skeletal Muscle Glycolytic Function in Aging Mice PMID 39569747
2,3
Defining Proximity Proteome of Histone Modifications by Antibody
DL
SIA Crosslinker 39028
N
延伸乙酰转移酶复合亚基 5（ELP5）基因
Fraxetin Inhibits the Proliferation and Metastasis of Glioma Cells by Inactivating JAK2/STAT3 Signaling PMID 33959183
KCTD1 Human Pre
Olevaprubart 3062612
OSI
L
A2AAR antagonist 1 1784491
m7GpppUpG 2638447
Sodium ricinoleate 5323
CST@NPs nanoparticle
2,2'
Tada3
VU661 37648
N
Vilazodone Intermediate 5
Discovery of a non
hCA/VEGFR
JBI
Cornulin 蛋白, Human (His)
The effect of centaurein on interferon
1,2
DTSSP Crosslinker 81069
Fmoc
(((9H
Isolugrandoside 221660
MCE
cGMP
Allosteric MEK inhibitors act on BRAF/MEK complexes to block MEK activation PMID 34470822
TRP1 蛋白, Human (HEK293, His)
endostatin
An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons PMID 28972160
PD 128907 123594
Gestational bisphenol A exposure induces fatty liver development in male offspring mice through the inhibition of HNF1b and upregulation of PPARγ PMID 32623698
Human Serum Albumin 抗体 (YA985)(PBS only)（Human Serum Albumin Antibody (YA985)(PBS only)）
beta III Tubulin 抗体 (YA586)(PBS only)（beta III Tubulin Antibody (YA586)(PBS only)）
Screening Based on Structural and Biological Verification of Stachyose as a PPARγ
MitoBloCK
Target guided synthesis of 5
SSX3 Human Pre
Chemical constituents of Ligusticum chuanxiong and their anti
H
Flurithromycin 82664
N
5
MoTP 57055
Antiparasitic agent
H
Effects of Combination of 1,25(OH) 2D 3 and TLR
PROTAC BRD3 degrader
LTD4 antagonist 2 107813
Pan
GYKI
A
Hesperetin triacetate
HEAL
LAMC1 Human Pre
T3
Discovery of SHR2415, a Novel Pyrrole
Hydroxyl
CDK7
D
2
Centmitor
MUC1 promotes lymph node metastasis in esophageal squamous cell carcinoma by downregulating DNAJB6 expression PMID 37584547
MCE
Nuclear fast red as highly sensitive off/on fluorescent probe for detecting guanine PMID 25159443
Vitamin K3
6
Lopinavir impurity 2 (Lopinavir impurity A)
Ramipril impurity 3 (Ramipril impurity L)
hsa
HDAC
MCE
Gambogellic acid 173867
Hedyotis diffusa injection modulates the ferroptosis in bladder cancer via CAV1/JUN/VEGFA PMID 39765005
3
Luciferase activator
Cloning and expression of the sucrose phosphorylase gene in Bacillus subtilis and synthesis of kojibiose using the recombinant enzyme PMID 29448943
4
P
Rotational spectroscopy of the atmospheric photo
Pterocarpans from Bituminaria morisiana and Bituminaria bituminosa PMID 12943781
Clinical efficacy and identification of factors confer resistance to afatinib (tyrosine kinase inhibitor) in EGFR
H
Z
Topoisomerase II inhibition and altered kinetics of formation and repair of nitrosourea and cisplatin
Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer PMID 33530952
D
BTB09089 245728
Utx Regulates the NF
NAD (P) 依赖性类固醇脱氢酶样（NSDHL）基因
MCE
Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression PMID 38622131
Z
BMS
Fmoc
糖脂转移蛋白（GLTP）基因
Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H
Soybean flour 68513
PSB
KU
Butamirate citrate 18109
5,5,5
Design, synthesis, and structure
N
Triumbelletin 7
S100a14
H
TNIP2 Human Pre
Identification of a new cannabidiol n
Rhapontigenin 3& 039;
PKHB1 1505523
RO5068760 947182
Expression of αV
Mono
Amorfrutin B 78916
Zanapezil fumarate 263248
(4S,11R)
Trovafloxacin 147059
Quercetin Improves Hippocampal Neurogenesis in Depression by Regulating the Level of Let
Iodothiouracil 5984
Interleukin
Identification and characterization of saikosaponins as antagonists of transient receptor potential A1 channel PMID 31782210
Aptiganel 137159
4
Ultra
Solifenacin impurity 7 (Solifenacin impurity B)
Fungal Metabolite Asperaculane B Inhibits Malaria Infection and Transmission PMID 32630339
Halictine 2
AHR 10718 96436
CD73
Nor Propranolol
Isoleukotoxin diol 73889
Antiparasitic agent
Ro 48
GW694481
Discovery of new hazimycin congeners from Kitasatospora sp. P07101 PMID 26713271
NADH
Behavior of quizalofop
DL
Anandamide, Acting via CB2 Receptors, Alleviates LPS
H
5
Neutrophil extracellular traps mediate TLR9/Merlin axis to resist ferroptosis and promote triple negative breast cancer progression PMID 37368176
Combining pharmacophore models derived from DNA
H
TAK
2
Identification of the stereochemical requirements in the 4
BRD4 promotes hepatic stellate cells activation and hepatic fibrosis via mediating P300/H3K27ac/PLK1 axis PMID 36907496
Congenital diaphragmatic hernia phosphodiesterase
LG
VISTA/B7
ACTR1B 抗体 (YA2686)（ACTR1B Antibody (YA2686)）
MCE
Protein phosphatase 2A restrains DLK signaling to promote proper Drosophila synaptic development and mammalian cortical neuron survival PMID 34923110
HADH 抗体 (YA6588)（HADH Antibody (YA6588)）
Cldn8 Rat Pre
Discovery of Novel, Potent, Brain
[Therapy of orthostatic dysregulation with gepefrin. Study with continuous telemetric blood pressure monitoring] PMID 4002776
BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor PMID 29386193
Methylamino
Network toxicology reveals collaborative mechanism of 4NQO and ethanol in esophageal squamous cell carcinogenesis PMID 40800605
(2R,3S)
Atf2 Rat Pre
Effects of LY295427, a low
Loxl2
DHHC5 facilitates oligodendrocyte development by palmitoylating and activating STAT3 PMID 34724258
IMM
A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis PMID 37588207
Design and synthesis of novel Hydroxamate and non
An Alternative Mechanism of Glutamate Dehydrogenase Inhibition by EGCG Promotion of Protein Degradation PMID 40573270
Xpc Rat Pre
GNAQ/GNA11 mosaicism causes aberrant calcium signalling susceptible to targeted therapeutics PMID 37802293
PIK75
ODN 20844 1964506
桃提取物 (Prunus persica L.)
Lgals4 Rat Pre
Stretched Vascular Endothelial Cells Polarized Neutrophils to N2 Type via TRPC1
Nectin2 Rat Pre
Pyruvate carboxylase and cancer progression PMID 33931119
LY393615 325819
H3B
B4galt1
Endothelial lipase promotes acute myeloid leukemia progression through metabolic reprogramming PMID 35263993
Exploring N
PON3 蛋白, Human (S50N, sf9, His)
Design and synthesis of novel and potent allosteric HIV
Fmoc
补体因子 D（CFD）基因
Desonide a review of formulations, efficacy and safety PMID 18549345
TOR signaling regulates liquid phase separation of the SMN complex governing snRNP biogenesis PMID 34161763
Structure
Screening, Discovery, and Optimization of the Natural Antitubercular Chlorflavonin from a Marine
IDEC
NLGN1 Human Pre
8a
Impact of genetic deficiencies of P
裂变，线粒体 1（FIS1）基因
Small
SPR741 1179330
Identification of a selective glucocorticoid receptor modulator that prevents both diet
MCE
Ubidecarenone
Sucrose octasulfate sodium 74135
Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors PMID 11595749
细胞色素 c 氧化酶亚基 4I1（COX4I1）基因
Potential Candidate Molecule of Photosystem II Inhibitor Herbicide
Lana yellow 4G 70247
Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing PMID 32739400
Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β
Csnk1a1 inhibition has p53
EPS8 样 3（EPS8L3）基因
Inactivation of Protein Tyrosine Phosphatases by Peracids Correlates with the Hydrocarbon Chain Length PMID 26112900
Me
Kaempferitrin's Dual Assault Inducing Apoptosis and Ferroptosis in Diffuse Large B
Bryonolic acid transcriptional control of anti
Cutamesine dihydrochloride 165377
Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy PMID 29444979
DBCO
ATR
Diethylstilbestrol
MCE
ACTH (4
Isomogroside VI 2496376
2
SAA4 蛋白, Human (His)
CRBN ligand
shisa 家族成员 5（SHISA5）基因
Neutrophils and the kallikrein
A
Boc
VOPP1 WW 结构域结合蛋白（VOPP1）基因
4
APP
Fmoc
PDGF
Antiviral agent 17 158227
Hypolipidemic Effect of Mannan in Mice with Acute Lipemia Induced by Poloxamer 407 PMID 27878733
Naringenin and Phytoestrogen 8
Melatonin Exerts an Anti
Unlocking the binding and reaction mechanism of hydroxyurea substrates as biological nitric oxide donors PMID 22519847
Dereplication Based Strategy for Rapid Identification and Isolation of a Novel Anti
AZ
HCV
Imidafenacin 170105
ARF1 (2
Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3) PMID 29244490
Membrane protein CRISPR screen identifies RPSA as an essential host factor for porcine epidemic diarrhea virus replication PMID 40736249
IL
FSH receptor antagonist 1 487064
RQIK
Digitoxin
Polyadenylic acid binding on cationic liposomes doped with the non
Long non
Varespladib
PMMB
MCE
LSD1
4ME 16 0 PS sodium
Decoupling actin assembly from microtubule disassembly by TBC1D3C
Vat Blue 2 29245
Research on the effect and underlying molecular mechanism of Cangzhu in the treatment of gouty arthritis PMID 35643303
FD
Protective Effects of Fisetin on Hepatic Ischemia
Clopidogrel thiolactone 1147350
Desacetylbufotalin (Bufogenin B)
MCE
7
Octyl azide 7438
3
Ethyl 5
DOPE
Panobacumab 885053
a
FLT3/ITD
Electrochemical treatment of the antibiotic sulfachloropyridazine kinetics, reaction pathways, and toxicity evolution PMID 22332959
Effect of imatinib on growth of experimental endometriosis in rats PMID 26773307
Eliglustat
Deciphering phenylalanine
Anti
Multi
PE_PGRS31
WEE1
Z
m
L
Design, synthesis and biological evaluation of novel naphthoquinothiazole derivatives as potent antitumor agents through inhibiting STAT3 PMID 38905884
Soquelitinib 2226636
D
Hidden Potential of Highly Efficient and Widely Accessible Thrombolytic Staphylokinase PMID 36039755
Deltasonamide 2 2088485
BI
Mechanism
Oxprenolol
Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks PMID 37463581
D
The Development of INT131 as a Selective PPARgamma Modulator Approach to a Safer Insulin Sensitizer PMID 18769500
TLR4 signaling pathway mediates the LPS/ischemia
ALOX15B Human Pre
MCE
Crystal structures of cephaibols PMID 14658793
(S,R,S)
Dexmedetomidine
4,6
5,6
Iopentol in urography. A clinical comparison between iopentol and metrizoate including delayed reactions PMID 1633050
STING agonist
NDMC101 1308631
Dopamine D4 receptor ligand 2 219125
CCG
Anti
5'
Brain and Body A Review of Central Nervous System Contributions to Movement Impairments in Diabetes PMID 31862690
MCE
Fasitibant chloride, a kinin B₂ receptor antagonist, and dexamethasone interact to inhibit carrageenan
PAF (C18) 74389
Characterization and determination of the major constituents in Belamcandae Rhizoma by HPLC
Lp
5
A small molecule inhibitor of Nox2 and Nox4 improves contractile function after ischemia
Nucleotide
Down
A zebrafish chemical suppressor screening identifies small molecule inhibitors of the Wnt/β
Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel PMID 32128418
Histone H3 (Di Methyl Lys27) 抗体 (YA7584)（Histone H3 (Di Methyl Lys27) Antibody (YA7584)）
Positive Feedback Regulation between KLF5 and XPO1 Promotes Cell Cycle Progression of Basal like Breast Cancer PMID 39888288
HRP2 determines the efficiency and specificity of HIV
Tyrosine kinase inhibitors. 5. Synthesis and structure
高迁移率基团核小体结合域 3（HMGN3）基因
Paralog
Ilexsaponin A 108524
Inhibition of proliferation, migration and invasion of RM
共994页
首页
上一页
941
940
939
938
937
936
935
934
933
932
931
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新