最近收录_第933页_生物活性分子
生物活性分子最近更新
Entadamide A 100477
Robipseudin A 1460737
TRAC 蛋白, Human (P.pastoris, His)
JH295 1311143
NAXE
Fmoc
CEBPD is a master transcriptional factor for hypoxia regulated proteins in glioblastoma and augments hypoxia induced invasion through extracellular matrix
Rbm7 Rat Pre
liberate granules
des
Suppressing CHD1L reduces the proliferation and chemoresistance in osteosarcoma PMID 33813077
Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo PMID 18680882
Cefditoren Pivoxil hydrochloride 1448435
2
Recent progress in development of cyclin
Malathion
Ganodermacetal 1443298
Azido
RITA1 Human Pre
Differential UVC radiation sensitivity in multidrug
RHCG Human Pre
Npbwr1 Rat Pre
Rac1 Inhibitor W56 TFA
Pharmacokinetics
Pumaprazole 158364
4
Zbtb12 Rat Pre
Hnrnpa2b1
Self
Platycoside F 314756
MCE
Fcer1a Rat Pre
Rapastinel acetate 491872
硫酸软骨素蛋白多糖 5（CSPG5）基因
Abemaciclib metabolite M20 2138499
Pheromone cCF10 inhibits the antibiotic persistence of Enterococcus faecalis by modulating energy metabolism PMID 39040910
Gastrin
GINS1 Human Pre
CENPC 抗体 (YA2227)(PBS only)（CENPC Antibody (YA2227)(PBS only)）
Pik3ip1 Rat Pre
RSV L
MCE
PKM Human Pre
Rgma
Folate
Fmoc
DHX30 Human Pre
Dibenzo
Structure
SLC39A6
CITED1 Human Pre
The Spirocyclic Imine from a Marine Benthic Dinoflagellate, Portimine, Is a Potent Anti
ACSL1 Aggravates Thromboinflammation by LPC/LPA Metabolic Axis in Hyperlipidemia Associated Myocardial Ischemia
CDK7
抑制剂
Biosynthesis of Strained Piperazine Alkaloids Uncovering the Concise Pathway of Herquline A PMID 27690412
5
5
Nintedanib improves bleomycin
SIRT6 抗体 (YA5214)（SIRT6 Antibody (YA5214)）
Nucleotide
5(S)
Olmesartan
L
A modified nucleotide in tRNA as a possible regulator of aerobiosis synthesis of cis
Nek2
1
MCE
JH
Fmoc
BTK
DJ
Hydroxyzine
S
N1
Triethylamine hydrochloride, 99%(T) 554
4
Glycyl
(Rac)
13
Enhanced interleukin
TOX
A novel thiol
EMAP 样 3（EML3）基因
COPS2 Human Pre
Verlamelin B
Chloridazon metabolite B1
DSPE
4,4′
SIRT5 inhibitor 8
MCE
(2R,2'R)
The hydrolysis of bile acid conjugates PMID 715825
Rbm15 Mouse Pre
MCE
SC57666 158959
N
Angeloyl
ERK1/2 inhibitor 8 2648368
D
Teleocidin A1 70497
(E)
Cell
DC
The PAD4 inhibitor GSK484 diminishes neutrophil extracellular trap in the colon mucosa but fails to improve inflammatory biomarkers in experimental colitis PMID 40459411
9,11
Ckap5 Mouse Pre
Fungal bis
SD
Cdc7
5
(Rac)
Smad5
CXCL9 抗体 (YA4202)（CXCL9 Antibody (YA4202)）
PROTAC ERRα ligand 2 2306388
Caraphenol A 354553
Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ER α to inhibit RANKL signaling PMID 33643823
Sleep deprivation engages the orexin/hypocretin system to regulate food reward seeking PMID 40613271
ANAPC5 Human Pre
Stereocontrolled synthesis of the PPAR
Phosphate acetyltransferase 9029
Obesity induces PD
Nacubactam 1452458
ML240 1346527
N
MIF2
Xanthohumol I 688360
Antiviral agent 18
Buffer Standards for the Physiological pH of the Zwitterionic Compound, ACES from 5 to 55°C PMID 20161482
解旋酶样转录因子（HLTF）基因
Antifungal agent 102
Linvencorvir 1808248
Carcinogenicity of 6
P2X7 Receptor Facilitates Cardiomyocyte Autophagy After Myocardial Infarction via Nox4/PERK/ATF4 Signaling Pathway PMID 40289672
HAPSBC 1376545
SLAIN 母题家族成员 2（SLAIN2）基因
Palmitic acid
Cathepsin C
N
Benzyl acetate
Kushenol E 99119
MR2
Structure
酸性磷酸酶 7，酒石酸抗性 (假定)（ACP7）基因
XPO6 Human Pre
Design, synthesis and evaluation of novel cycloalkylthiophene
Z
DAPL1 Human Pre
TP
Design, Synthesis, and Characterization of 4
D
Ro 106
Ckap5 Rat Pre
Development of novel tetrahydroisoquinoline
LINGO1 Human Pre
RhoGDI 抗体 (YA4080)（RhoGDI Antibody (YA4080)）
7
合成蛋白（SYBU）基因
GIT2 Human Pre
Vimseltinib 1628606
4
BMS564929
BIIB042, a novel γ
20(S)
Casein Kinase Substrates 3 154444
MCE
Tef
Benzyl
Vimseltinib
Ionizable Drugs Enable Intracellular Delivery of Co
Targeted citrullination enables p53 binding to non
tert
N
MCE
2,2',2'',2'''
Sodium lauryl sulfoacetate 1847
Minpp1
Structure
3
NMDA receptor antagonist 5 2415998
1
Stevioside D 1310055
Nusinersen ameliorates motor function and prevents motoneuron Cajal body disassembly and abnormal poly(A) RNA distribution in a SMA mouse model PMID 32612161
AA9 2134114
Carvacrol methyl ether 6379
Phorbol 17673
A2AAR/hMAO
BM 957 1391107
Inhibitor of MYC identified in a Kröhnke pyridine library PMID 25114221
TRAF3IP3 Human Pre
Hydroxymycotrienin A 178550
Metabutoxycaine 3624
HET0016 decreases lung metastasis from breast cancer in immune
Triethylene glycol diacetate 111
Grifolin 6903
Activity of OP0595/β
Influence of subtilisin on the adhesion of a marine bacterium which produces mainly proteins as extracellular polymers PMID 18489561
Synthesis, computational studies, antimycobacterial and antibacterial properties of pyrazinoic acid
I
Boc
IDO
Methyl (2R)
IL
hsa
DDAO 118290
Distinct properties and activation of hexameric and heptameric Pannexin 1 channel concatemers PMID 39704698
tert
Arizonin A1 108890
Dhx30 Rat Pre
Axinelline A 1593741
H
Role of glutathione in the biliary excretion of the arsenical drugs trimelarsan and melarsoprol PMID 10751546
GWP
(E)
Anxiolytic homophthalazines increase Fos
Design, Synthesis, in Silico and in Vitro Dipeptidyl Peptidase
Vidarabine monohydrate 24356
PF
MCE
Estrogen signaling An emanating therapeutic target for breast cancer treatment PMID 31129450
5& 039;
22
Ccl8
CCT077791
Dhx30 Mouse Pre
Identification of a novel allosteric binding site on the catalytic domain of NF
First iron(II) organometallic compound acting as ABCB1 inhibitor PMID 37187089
(2R,3S)
FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer rationale for a triple blockade of ER, CDK4/6, and FGFR1 PMID 33579347
Dual mTORC1/mTORC2 Inhibition as a Host
Decr1 Rat Pre
7
IP/Co
ERLIN1 Human Pre
3
EG36
Noladin ether
Lilrb4a
BCPyr 2669844
ELOVL6 deficiency aggravates allergic airway inflammation through the ceramide
Hypoxanthine
YY173 330550
HL
含 V 集和跨膜结构域 2 个样（VSTM2L）基因
Tripterygone 138570
SEMA3G Human Pre
In vitro synthesis of arachidonoyl amino acids by cytochrome c PMID 19683594
(((9H
Phase 1
HNRNPA1 蛋白, Human (His)
Combining lavendustin C and 5
Tox3 Rat Pre
GIN1 Human Pre
GDNF
Ethyl acetylglycinate 1906
TMB dihydrochloride 64285
MCE
MCPG sodium 1303994
QLT0074
RET
MCE
GNG13 蛋白, Human (His)
(R)
Foscenvivint 1422253
氯化物电压门控通道 Kb（CLCNKB）基因
CLEC4C 蛋白, Cynomolgus (HEK293, hFc)
Characterization of LDD
EGFR
Synthesis, stereoelectronic characterization and antiparasitic activity of new 1
MCE
Discovery of a new allosteric inhibitor for human dopamine transporter by physics
Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3
Design and synthesis of a series of melamine
NT5DC2 knockdown inhibits colorectal carcinoma progression by repressing metastasis, angiogenesis and tumor
1,5
The melanocytic protein Melan
The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf
Maleylacetoacetate isomerase/GSTZ1 蛋白, Human (N
PDPK1 抗体 (YA5866)（PDPK1 Antibody (YA5866)）
Arabinose
The prevention of the staurosporine
PROTAC SMARCA2 degrader
Piperidine
Cortisol sulfate sodium 1852
IMP 243 391267
Paclitaxel octadecanedioate 2089211
Organ
RNF144B Human Pre
Oral azoxystrobin driving the dynamic change in resistome by disturbing the stability of the gut microbiota of Enchytraeus crypticus PMID 34844364
Synthesis and pharmacological in vitro and in vivo profile of 3
Roles of different forms of cytochrome P450 in the activation of the promutagen 6
Complement Factor D as a Strategic Target for Regulating the Alternative Complement Pathway PMID 34566967
Phenylalanine
泛素结合酶 E2 E1（UBE2E1）基因
Nr4a1
Photobiomodulation therapy for hair regeneration A synergetic activation of β
Differential effects of inhibitors on the gamma
ACTH(4
Boc
Real
Hdm2 E3 ligase inhibitor 1 414905
Click synthesis of a polyamidoamine dendrimer
GSK2181306A 2579173
Plasma 2
真核翻译起始因子 1B（EIF1B）基因
含 ELMO 域 2（ELMOD2）基因
Hydrocortisone phosphate sodium (Standard) (氢化可的松磷酸钠 (标准品))
The Chemokine
Spast
NSUN4 抗体 (YA6684)（NSUN4 Antibody (YA6684)）
MKC
Phospho
Telekin 6752
((4
ADRM1 Human Pre
Escholtzine perchlorate 77790
Three classes of glucocerebrosidase inhibitors identified by quantitative high
MetRS
RRAD、Ras 相关糖酵解抑制因子和钙通道调节因子（RRAD）基因
Fgf21
α
A small
Yck2
Sord Mouse Pre
BS3 Crosslinker disodium 127634
InCl3
Ketoconazole
Cytotoxic effects of recombinant proteins enhanced by momordin Ic are dependent on cholesterol and ganglioside GM1 PMID 37086901
Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress
Circulating exosomes repair endothelial cell damage by delivering miR
Structural selectivity of human SGLT inhibitors PMID 21940664
Efna1 Mouse Pre
CD46 Human Pre
Central action of insect neuropeptide, periplanetin CC
南洋参提取物 (Polyscias fruticosa (L.) Harms)
Vipr1
Slc39a6 Rat Pre
PA
SOX30 Human Pre
LGALS4 Human Pre
Bagougeramine B 104840
(R)
Nonpeptide ligands of neuropeptide FF current status and structural insights PMID 22709252
Glioma cells produce soluble PD
Salidroside 3
泛素结合酶 E2 W（UBE2W）基因
KCNJ2 Human Pre
MACROD1 Human Pre
2
BMS
Oxomemazine hydrochloride 4784
Selective Targeting of Breast Cancer by Tafuramycin A Using SMA
LILRA6 Human Pre
Apoptotic induction by pinobanksin and some of its ester derivatives from Sonoran propolis in a B
BMS
Adefovir dipivoxil efficiently inhibits the proliferation of pseudorabies virus in vitro and in vivo PMID 33422610
Development of PI3K/mTOR
Brachyoside B 86764
Muc5ac
溶质载体家族 39 成员 6（SLC39A6）基因
Todralazine (Ecarazine)
In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs PMID 17715126
(R)
木通提取物 (Akebia quinata (Houttuyn) Decaisne)
EG35 2061310
Identification of a novel α
Molecular dynamics simulations of human α
GKL003 1445801
Anti
Debio
STING antagonist
Identification of a queen and king recognition pheromone in the subterranean termite Reticulitermes flavipes PMID 29555778
IWR
Anti
Hazimycin 5 84894
M8
Mixed lineage kinase domain
Cdyl2 Rat Pre
The role of STIM1/ORAI1 channel in the analgesic effect of grain
L
LDC3140 1453833
Pharmacokinetics and pharmacodynamics of LGD
Role of signalling molecules in behaviours mediated by the δ opioid receptor agonist SNC80 PMID 29278419
IL
Inhibitory Activities of Stauntonia hexaphylla Leaf Constituents on Rat Lens Aldose Reductase and Formation of Advanced Glycation End Products and Antioxidant PMID 28326319
Relebactam sodium 1502858
BC 197 115295
Cyclo(Ala
4
Butyryl
Effects of 1α,25
Combinatorial Pharmacophore
Hepatitis E viral infection regulates estrogen signaling pathways Inhibition of the cAMPK
Synthesis and evaluation of N
The mapping of the Lyn kinase binding site of the common beta subunit of IL
GDF7 Human Pre
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β
Prolactin and estrogen up
MC
Discovery of a novel class of benzimidazoles as highly effective agonists of bone morphogenetic protein (BMP) receptor signaling PMID 35840622
Strombine 56857
IL
PIK3IP1 Human Pre
The selective aryl hydrocarbon receptor modulator 6
Age
Bioactive polyketides from Peperomia duclouxii PMID 17547458
Molecular detection of Chlamydia trachomatis and other sexually transmitted bacteria in semen of male partners of infertile couples in Tunisia the effect on semen parameters and spermatozoa apoptosis markers PMID 25019616
Acceleration of gastrointestinal transit by momordin Ic in mice possible involvement of 5
Pnrc1
Mlf1 Rat Pre
An improved method for quantification of cholesterol and cholesteryl esters in human monocyte
6
Vcan Rat Pre
Development of Potent Mcl
Inhibition of lanosterol synthase linking with MAPK/JNK signaling pathway suppresses endometrial cancer PMID 39922821
Droxidopa alters dopamine neuron and prefrontal cortex activity and improves attention
Preclinical immunological characterization of rademikibart (CBP
Rhodamine
Vsir Rat Pre
Granulocyte colony
Vinculin 蛋白, Human (HEK293, His)
Characterization of differential pore
calpain 1
Characterisation of a Novel Anti
Matrix metalloproteinase 2
GSTZ1 Human Pre
Caffeoylquinic acid derivatives rich extract from Gnaphalium pensylvanicum willd. Ameliorates hyperuricemia and acute gouty arthritis in animal model PMID 28623927
Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells PMID 11536386
Matr3
Efficient and specific cardiac IK₁ inhibition by a new pentamidine analogue PMID 23625347
Magi1
hCA/VEGFR
Fmoc
1
Comprehensive quantifications of tumour microenvironment to predict the responsiveness to immunotherapy and prognosis for paediatric neuroblastomas PMID 38691920
Potential of Small Molecule
Advantage of MALDI
Pancreatic β
rac
Synthesis and antitumor evaluation of benzoylphenylurea analogs PMID 15081011
The tumor
Quizalofop
Optimization and development of a high
Photodynamic therapy with conventional and PEGylated liposomal formulations of mTHPC (temoporfin) comparison of treatment efficacy and distribution characteristics in vivo PMID 24143087
HNF4A negatively regulated posterior capsular opacification via transcriptional inhibition of MMP2 PMID 36988559
CLEC9A Human Pre
Ak9 Rat Pre
Development of small
Diethyl [2,2' 6',2''
Cassane
8
Targeting of α(v)
Nitrocaphane (At
Thermally induced cyclization of L
EGR1 regulates oxidative stress and aldosterone production in adrenal cells and aldosterone
Hydroxy Bosentan
Screening of protonstatin
Alloxan decreases intracellular potassium content of the isolated frog skin epithelium PMID 11544140
DTL
Involvement of reactive oxygen species in adaphostin
In vivo Stat1 Mouse Pre
Reactive oxygen species inactivation of surfactant involves structural and functional alterations to surfactant proteins SP
An Analysis of Successful Hit
Chamaejasmenin B, a novel candidate, inhibits breast tumor metastasis by rebalancing TGF
Pkm Rat Pre
In vivo Igkc Mouse Pre
AZD9150, a next
PD 151746 181765
Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2
TLC388 1432468
Fc ε RIα 抗体 (YA9510)（Fc ε RIα Antibody (YA9510)）
Selectivity is species
Functional excitatory synapses in HEK293 cells expressing neuroligin and glutamate receptors PMID 12930820
Pyrotinib
Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration
The inward rectifier current inhibitor PA
Demethylzeylasteral (T
A diacetylenic spiroketal enol ether epoxide, AL
(±)
S
Minoxidil sulfate induced the increase in blood
Resorufin butyrate as a soluble and monomeric high
New cell cycle checkpoint pathways regulators with 2
DPP
Oral efficacy of a respiratory syncytial virus inhibitor in rodent models of infection PMID 15215093
Kaempferol
Verapamil
1,2
Tescalcin modulates bone marrow
An Open
The therapeutic effect of fraxetin on ethanol
Purinergic P2X(7) receptor antagonists Chemistry and fundamentals of biological screening PMID 19540765
Methyl L
2
Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property
DNA Topoisomerases PMID 26435256
Lactonamycin 182234
Herquline A 71812
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