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ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer PMID 36056253
Co
Exploration of the antitumor effect and mechanism of gambogic acid on osteosarcoma through network pharmacology and experimental pharmacology study PMID 40594358
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF
f25, a novel synthetic quinoline derivative, inhibits tongue cancer cell invasion and survival by the PPAR pathway in vitro and vivo PMID 38278315
BTF3 confers oncogenic activity in prostate cancer through transcriptional upregulation of Replication Factor C PMID 33414468
Sporoderm
LncRNA FLG
SLFN11 inhibits hepatocellular carcinoma tumorigenesis and metastasis by targeting RPS4X via mTOR pathway PMID 32292519
Metabolomics and integrated network pharmacology analysis reveal Tricin as the active anti
YiQiChuTan formula (YQCTF) inhibit the progression of non
Cancer
Bufalin A promising therapeutic drug against the cisplatin
A COX
Blocking of SIRT7/FOXO3a axis by miR
LncRNA MALAT1 increases the stemness of gastric cancer cells via enhancing SOX2 mRNA stability PMID 31037832
PKMYT1 inhibitor
β
MCHR1 (GPR24)
cell biology
Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance PMID 28708938
EN40
Phospho
SLC30A8
ROS kinases
(1E,2E)
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) 211426
1,2
DMPG
AVI6451
human heparinase
Shepherdine
Armeniaspirol B 1206881
S
(S)
Limitations in the Use of Fluorescein Diacetate/Propidium Iodide (FDA/PI) and Cell Permeable Nucleic Acid Stains for Viability Measurements of Isolated Islets of Langerhans PMID 20814586
TPNQRQNVC
Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2 PMID 37523859
Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor PMID 28230359
Deacetylasperulosidic Acid 14259
Pomalidomide 4'
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS
phenylpropanoid glycoside
PLLA10000
Synthesis of 2,6
Br
TMC353121 857066
Surface Affinity of Tetramethylammonium Iodide in Aqueous Solutions A Combined Experimental and Computer Simulation Study PMID 37276239
Antibiotics from basidiomycetes. XIII. The alliacols A and B from Marasmius alliaceus (Jacq. ex Fr.) Fr PMID 7198113
antifungal activities
Neuropharmacology of the muscarinic antagonist telenzepine in myenteric ganglia of the guinea
YM435
GRIN2B gain of function mutations are sensitive to radiprodil, a negative allosteric modulator of GluN2B
Intestinal Absorption Profile of Three Polygala Oligosaccharide Esters in Polygalae Radix and the Effects of Other Components in Polygalae Radix on Their Absorption PMID 31354847
CD2
Mitoridine 3911
Imidafenacin has no influence on learning in nucleus basalis of Meynert
Anti
HPGDS 蛋白, Human
Exosomes secreted from M2
Suppression of Heterogeneous Nuclear Ribonucleoprotein C Inhibit Hepatocellular Carcinoma Proliferation, Migration, and Invasion via Ras/MAPK Signaling Pathway PMID 33937074
Chemosensitization of non
TACE antagonists blocking ACE2 shedding caused by the spike protein of SARS
Characterization of the recombinant human prostanoid DP receptor and identification of L
1,3
Antitumor agent
Nur77
Competitive antagonist
BY1023 (Standard)
Pterosin O 54854
PF
Tepoxalin a dual cyclooxygenase/5
Docebenone
BC
ML 901
Homocarnosine 3650
UAB30
Thiol
2
Specificity, affinity and efficacy of iota
Capmatinib dihydrochloride hydrate 1865733
C1s
Phospho
Bromoacetamido
C258
HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF
4
Diflorasone diacetate 33564
Neutrophils suppress osteogenic differentiation of Gli1+ stem cells via neutrophil extracellular traps and contribute to bone loss in periodontitis PMID 39489114
Curcumin
Classification of active and weakly active ST inhibitors of HIV
Crystal Ponceau 6R
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121) PMID 18254606
P
18
Sleeping Beauty mRNA
The 5HT(1B) receptor agonist, CP
Development of a high
Necrosulfonamide
spiperone
Axinysterol
C26 0 methyl ester
NH2
AL39324
6
NASA
3
Clausenalansine B
Quinolinyl
Discovery of 6
Striatal tissues
Izumo1r Mouse Pre
含 PDZ 结构域 2(PDZD2)基因
Gfpt1
BDP 630/650 hydrazide hydrochloride 2183473
Bcl2 样10(Bcl2l10)基因
Tmprss11d
PRMT7 Human Pre
A68930 130465
Efhd2
Phenoxyethanol
DL
Biotin
Ly6h Mouse Pre
4
(S)
AGN
Azo SM
Steap2
Prdm2
dithioethane
YM
BMS 986470
R162
LBH589
Ca 2 sensitive
MCE
nitrite analysis
MCE
lymph node cell
5
zebrafish AD model
mutation specificity
MA
A model for binding of an antifreeze polypeptide to ice PMID 1489916
4
MCE
Phospho
Methyl 8(Z),11(Z),14(Z)
EML741 2328074
EML741
Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors Rational Design, Synthesis, Biological Evaluation, and Co
EML 741
12S
沙丁胺醇
Oxpentifylline
(R)
prokaryotes
hGIIA
反式
Viral infections in humans and mice with genetic deficiencies of the type I IFN response pathway PMID 33729549
TNF
Antitrypanosomal agent
3
Crystal Ponceau 6R 2766
Analysis of nitrite and nitrate in biological fluids by assays based on the Griess reaction appraisal of the Griess reaction in the L
Bovinic acid 2540
Pgrmc1
The Pseudomonas aeruginosa Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing PMID 32156827
Sut
Ipatasertib
5''
Dnmt1 抗体 (YA3915)(Dnmt1 Antibody (YA3915))
visceral sensory information
4
Phospho
SLC30A8 Human Pre
PLIN4 Human Pre
Peptide KN
Zelandopam free base 139233
Inhibitory peptide analogs derived from a major uveitogenic epitope protect from antiretinal autoimmunity by inducing type 2 and regulatory T cells PMID 18495789
Tenatoprazole 113712
1
ZNF219 Human Pre
XPNPEP1 Human Pre
Harnessing the Deubiquitinase USP1 for Targeted Protein Stabilization PMID 40252079
Synthetic calanolides with bactericidal activity against replicating and nonreplicating Mycobacterium tuberculosis PMID 24694175
SG
polyamine compound
murine macrophage RAW 264.7 cells
A pyridoxine cyclic phosphate and its 6
4
Phospho
ssVACV
3
3
2,2′
D
JD128
screening
Echinoside A
EZH2 ligand
Quantification of dsDNA using the Hitachi F
Adamts1
eleuthoside
Efhd2
tau 微管蛋白激酶 1(TTBK1)基因
Sh3gl3
GLP
β
1
Effects of N
DMPE
MicroRNA
MicroRNA
In vivo antioxidant activity of deacetylasperulosidic Acid in noni PMID 24371540
Antiarrhythmic potency of procainamide and N
S
N,N
GPR34
Toll样受体 1(Tlr1)基因
RIOK2
Ro 24
Arl2bp
Acid blue 62
Sapindoside B 30994
干扰素调节因子 2 结合蛋白 2(IRF2BP2)基因
Potential Anti
IDH
二十六酸甲酯
L
SFE 27 0
Elavl4 Rat Pre
Ac
10
Sord
Pde4d
Gstm1
High
Cdkl4
topoisomerase 2α
L
EGIS
Parp12
Metoprolol impurity 2
3
Phospho
YM 435
RESCA
顺式地黄苷
PLLA10000
28
LAT
The rational search for PDE10A inhibitors from Sophora flavescens roots using pharmacophore‑ and docking‑based virtual screening PMID 29115449
GSK
ORG
OP 1690
R
metallob
DMPG
ALDH1A1
YM 60828
NCI
雷贝拉唑(Standard)
The 5
Guanfu base G
Isolation of high
Echinoside A 75410
PPT1 蛋白, Human (HEK293, His)
alpha
Rhodblock 1a
Ferulic Acid Improves Synaptic Plasticity and Cognitive Impairments by Alleviating the PP2B/DARPP
PKA II
TG101348
Ceic acid methyl ester
CACNB3 Human Pre
Activation of liver X receptor alleviates ocular inflammation in experimental autoimmune uveitis PMID 24699378
5
泮托拉唑(Standard)
Pyrazinamide
Atracurium Besylate and other neuromuscular blocking agents promote astroglial differentiation and deplete glioblastoma stem cells PMID 26575950
DAPK2 Human Pre
striatal
The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro PMID 30781809
phoBET
<i>Dolichos trilobus</i>
BTB06584 219793
Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K
CD2
NG,NG
Effect of SMP
FAM
HSG
1
5,5& 039;二溴
1,3
Trichodimerol 145174
Methyl 5(Z)
JD 128
Capacitative calcium entry as a pulmonary specific vasoconstrictor mechanism in small muscular arteries of the rat PMID 12967939
Duloxetine impurity 3 hydrobromide 949096
diorcinol
Tigloylgomisin H 66069
Arisugacins, selective acetylcholinesterase inhibitors of microbial origin PMID 9535168
VTP34072
Tarp regulates early Chlamydia
Detection of protein ubiquitination PMID 19692941
5
Ac
folic
Sulfamonomethoxine 1220
Discovery and characterization of phenoxyacetic acid derivatives as potential antiepileptic agents PMID 41113602
Pigment Red 188 61847
Degradation of IRF6 by TRIM59 in tumor cells triggers PGM1
Basic red 9
Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors PMID 32853870
Pyclen
Biomimetic virus
Discovery of Novel α,β
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling PMID 33783220
Small Molecule
ML
Anti
ALT
The Effect of Citicoline on Ethambutol Optic Neuropathy Histopathology and Immunohistochemistry Analysis of Retina Ganglion Cell Damage Level in Rat Model PMID 36074092
RGH
Oral delivery of 1,3
Harnessing potential COX
Adamts14 Mouse Pre
(R)
Boc
J9Z38
Rh
Synthesis and in vitro exploration of the 8
polysaccharide labeling
10
punishment
Quisqualate
3
Fontimonas thermophila Alkane Monooxygenase (FtAlkB) Is an Alkyl Fluoride Dehalogenase PMID 40052925
Octadecaneuropeptide 95237
SG3376
5,5& 039;
AGN 190383
六臂PEG马来酰亚胺 (MW 600)
DNMT2 蛋白, Human (sf9, GST)
Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation PMID 8182146
H
Aβ
Diheptanoyl Thio
Proteolysis targeting chimeras (PROTACs)
六臂PEG马来酰亚胺 (MW 10000)
RAD51
DWP14012
GLP
Pyridoxine
ZQ16
Bacoside A2 58798
Benzoylformic acid
Anti
Glutamate Dehydrogenase
rat parietal cells
Metoprolol impurity 14
rat primary cortical neurons
3′
Mirabegron 223673
Pyrimidine
D
PDE10
Discovery and Characterization of a Novel Small
Antibiotic K4
Palladium(II) 5,10,15,20
maturational cleavage
Apremilast impurity 1 (Standard)
17 0
Antifungal constituents of Melicope borbonica PMID 15305313
hyperandrogenism
山崎草莓营养液
pCHK1(Ser345)
BTB06584
4
rat NK
PSB
BVT 74316
GBR 12783
VPC
CGP
CGI17341
(2R,3R,11bR)
Pyrrolo[2,3
Estrogen receptor‑β‑dependent effects of saikosaponin‑d on the suppression of oxidative stress‑induced rat hepatic stellate cell activation PMID 29286085
Pro
RNA 靶向生物活性化合物库
Design, synthesis and biological evaluation of novel kojic acid triazole hybrids as tyrosinase inhibitors and antibrowning agents PMID 40301405
ROBO1
DMPE
MCE
MCE
MCE
MCE
CGS 26303 154116
[Studies on chemical constituents in the mycelia from fermented culture of Flammulina velutipes] PMID 15719637
2,6
IQTub4P 2376321
3
Characterization of the ORL(1) receptor on adrenergic nerves in the rat anococcygeus muscle PMID 10991930
YAP1
Unde venisti PGRMC? Grand
Synthetic derivatives of the natural product 13
Neuroprotective and anticonvulsant effects of EGIS
Dexamethasone impurity 6 72559
Reduced toxicity and superior therapeutic activity of a mitomycin C lipid
Polyketides with Immunosuppressive Activities from Mangrove Endophytic Fungus Penicillium sp. ZJ
碗蕨科提取物 (Dennstaedtiaceae)
CP5736
Novel kojic acid
Unraveling the interaction of pyranocoumarins with P
4
complete estrogen receptor antagonist
RHC 80267 (Standard)
Carboxyl PEGylation of magnetic nanoparticles as antithrombotic and thrombolytic agents by calcium binding PMID 36780849
estrogen receptor
Taxol induces caspase
4
Pyridin
A protein folding molecular imaging biosensor monitors the effects of drugs that restore mutant p53 structure and its downstream function in glioblastoma cells PMID 29765555
Successful treatment of AIDS
Wfdc2
CS
DMT
Antimalarial agent 41
Quinolinyl
Antimycobacterial agent 7
Tlr5
Eupalinolide C
Antibacterial agent 339
Acid yellow 199 70865
Ceotic acid methyl ester
Ethylene dimethanesulfonate 4672
Extraction and in vitro screening of potential acetylcholinesterase inhibitors from the leaves of Panax japonicus PMID 28734162
Endothelial progenitor cell
Cytoskeletal remodeling
Design and synthesis of novel tranilast analogs Docking, antiproliferative evaluation and in
15
Adamts5
Design, synthesis and biological evaluation of novel guanidine
HL
K
FABP4 抗体 (YA449)(FABP4 Antibody (YA449))
gravis
Pectate Lyase, Aspergillus sp.
(±)
Ferroptosis
ABS
GDF
lytic cycle
MK 0791
Insecticidal agent 32 (杀螨腙)
ML 098
Phospho
Antifungal Activities of Dimeric Sesquiterpenes, Shizukaols C and F, Isolated from Chloranthus japonicus Sieb PMID 28535608
Voltage
Eleuthoside B
Polyoxin
A1bg
RAMOS cells
MicroRNA
TLR2/1 agonist
CP2
MicroRNA
Effect of polyoxin D on chitin synthesis and septum formation in Saccharomyces cerevisiae PMID 4604393
Athyrium multidentatum
Immunoproteasome as a Target for Prodrugs PMID 40098355
JD128
Phosphoenolpyruvic acid monosodium
Polyoxin D
Polyoxin D 22976
Acid blue 62 4368
RIOK
(S,R,S)
Cytoproliferative and Cytoprotective Effects of Striatisporolide A Isolated from Rhizomes of Athyrium multidentatum (Doell.) Ching on Human Umbilical Vein Endothelial Cells PMID 27669209
Monitoring the Immunoproteasome in Live Cells Using an Activity
Convolvulus scammonia extract 84775
In vitro and in vivo activity of carbamate
Discovery and development of anti
Antibiotic K
Glycyl
Scopolamine butylbromide 149
ε
Antitrypanosomal agent 28
proangiogenic peptide
Xpnpep1 Rat Pre
GSK 2245035
EN 40
兰索拉唑N
DMT
Isomeric inversion of ibuprofen (R)
mmu
Sut8701
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