最近收录_第929页_生物活性分子
生物活性分子最近更新
Naringenin
Picroside I and Picroside II from Tissue Cultures of Picrorhiza kurroa PMID 29333043
Occurrence of avenanthramides and hydroxycinnamoyl
Neuroprotective effects of saikosaponin
Minoxidil sulfate is the active metabolite that stimulates hair follicles PMID 2230218
Galectin
A Pan
Multiple drug transporters contribute to the brain transfer of levofloxacin PMID 36253925
N
Neutrophil extracellular traps promote M1 macrophage polarization in gouty inflammation via targeting hexokinase
Estramustine Phosphate Inhibits TGF
Defective FXR
ADCT
Atogepant for the Preventive Treatment of Migraine PMID 34407343
Enhancing spleen
NSC 23925B 1369591
Phosphate monobasic
Dimeric polyphenols to pave the way for new antimalarial drugs PMID 37122550
Antihyperalgesic effects of a novel muscarinic agonist (LASSBio
In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC 680410 against human leukemia and glioblastoma cell lines PMID 12451475
NF
DSPE
L
BRCA2 prevents PARPi
Remodelin 949912
Human haptoglobin, low endotoxin (人结合珠蛋白,低内毒)
The Protective Effect of Resveratrol on Concanavalin
An mTOR inhibitor discovery system using drug
Chamaejasmenin B, an Inhibitor for Metastatic Outgrowth, Reversed M2
GDC
Costunolide 553
(+)
Vitronectin 83380
Methylamino
Cappariloside A shows antiviral and better anti
Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms PMID 25580584
Autophagy
A role for BET proteins in regulating basal, dopamine
Selective DNA
PIQ2
Ccl27a
COTI
Network Pharmacology and Experimental Validation Reveal Sishen Pill's Efficacy in Treating NSAID
Mibavademab 2305770
MRS 5980 1639420
Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago
Defensin NP
P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor
Prime
Colistin B
Demethylzeylasteral inhibits glioma growth by regulating the miR
The NK1 receptor antagonist N
1,4
Kinevac (sincalide for injection)/Squibb Diagnostics PMID 1932168
Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells PMID 16822295
13 0 Lyso PI
Nedd4l
Discovery of 2
Selective Photoaffinity Probe for Monitoring Farnesoid X Receptor Expression in Cultured Cells PMID 35853240
Peretinoin 81485
Ultrapotent Inhibitor of Clostridioides difficile Growth, Which Suppresses Recurrence In Vivo PMID 32960605
Pardoprunox 269718
LIF 受体亚基α（LIFR）基因
Dual effects on HDL metabolism by cholesteryl ester transfer protein inhibition in HepG2 cells PMID 12604506
CUMS
Reduced Zn2+ promotes retinal ganglion cells survival and optic nerve regeneration after injury through inhibiting autophagy mediated by ROS/Nrf2 PMID 38134974
Anisylacetone
YB
Lack of efficacy of an inhibitor of PDE4 in phase 1 and 2 trials of patients with nonalcoholic steatohepatitis PMID 24530600
Gestational exposure to PM2.5 disrupts fetal development by suppressing placental trophoblast syncytialization via progranulin/mTOR signaling PMID 38387595
Toxicity of penicillic acid for rat alveolar macrophages in vitro PMID 2430790
PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase PMID 26503893
In vivo anti
Trospium chloride 10405
Isoprothiolane
Louisianin D 171784
Discovery of Diaryl Piperidone
Mesutoclax 2760536
Discovery of NVP
Design, synthesis, antiviral and cytostatic activity of ω
Bisphenol C induces developmental defects in liver and intestine through mTOR signaling in zebrafish (Danio rerio) PMID 36822516
Slime Control Agent
A bibliometric analysis of PROTAC from 2001 to 2021 PMID 36274273
Kinetics of human serum butyrylcholinesterase and its inhibition by a novel experimental Alzheimer therapeutic, bisnorcymserine PMID 16988481
Dansyl
Involvement of cytochrome P450
Controlled Activation of TRPV1 Channels on Microglia to Boost Their Autophagy for Clearance of Alpha
Lin28B 抗体 (YA709)（Lin28B Antibody (YA709)）
2
Effective treatment of liver metastases with photodynamic therapy, using the second
Development of a small compound that regulates the function of a maltodextrin
From TGN1412 to TAB08 the return of CD28 superagonist therapy to clinical development for the treatment of rheumatoid arthritis PMID 27586803
Alpha
Gastric
Activity
CRBN ligand
Momordicoside P 1011726
H
Cathepsin G Inhibitor I 429676
Selective Azapeptide CD36 Ligand MPE
Theralizumab 906068
Ppp3r1
N
GPNMB marks a quiescent cell population in melanoma and promotes metastasis formation PMID 40528051
A novel human CC chemokine PARC that is most homologous to macrophage
雌激素受体 2 (β)（Esr2）基因
L
Neuroprotection of paliperidone on SH
CD40L/CD154/TRAP 蛋白, Rat (HEK293, Fc)
S
TLR7/8 agonist 6 2115702
(1R,2R)
Oryzalin 19044
Effects of estrogen on social recognition and oxytocin regulating synaptic plasticity PMID 39952542
Navarixin 473727
Mechanism of riboflavine uptake by Caco
Calcitriol Impurities D 103656
Tilianin enhances the antitumor effect of sufentanil on non
ATOX1 Promotes Hepatocellular Carcinoma Carcinogenesis via Activation of the c
Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal neurons of rat sensorimotor cortex PMID 12626613
Dose
Discovery of BPR1K871, a quinazoline based, multi
Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR
The DAZL family proteins are PABP
Embryotoxicity of oral administered chlorothalonil in mice PMID 16607634
Escholtzine perchlorate
1,1,1
Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo PMID 22348348
Bazedoxifene Suppresses Intracellular Mycobacterium tuberculosis Growth by Enhancing Autophagy PMID 32269154
PIM
Construction and Evaluation of Novel Dual
pro
Chisocheton compound F 157376
Cblc
Il36rn Mouse Pre
DC
Targeting chondroitin sulfate suppresses macropinocytosis of breast cancer cells by modulating syndecan
FGF4 Human Pre
DDRGK1 Human Pre
ONECUT3 Human Pre
Protective effect of madecassoside on H2O2
Dehydrotrametenolic acid methyl ester, a triterpenoid of Poria cocos, alleviates non
Carboxyamidotriazole
1
Mimulone
Mutant mice with rod
Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells PMID 33452240
Salvianolic acid B improved insulin resistance through suppression of hepatic ER stress in ob/ob mice PMID 32265029
Threonine Deficiency Increases Triglyceride Deposition in Primary Duck Hepatocytes by Reducing STAT3 Phosphorylation PMID 39125712
S
Bullatine A exerts anti
1
Adrenocorticotropic Hormone (ACTH) (1
Effect of madecassoside and catalpol in amelioration of insulin sensitivity in pancreatic (INS
Development of 18F
Carboxyamidotriazole alleviates pannus formation and cartilage erosion in rats with adjuvant arthritis PMID 37809969
LPA5 antagonist 3 1664336
Development of a photoactivatable allosteric ligand for the m1 muscarinic acetylcholine receptor PMID 25188871
TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model PMID 26959227
Inhibition of Ca2+
(+)
Analysis of responses to adrenomedullin
LQB
MRPL13 Human Pre
Taurine
14
Decreased Expression of Plakophilin
ML338
Cedrol Enhances Extracellular Matrix Production in Dermal Fibroblasts in a MAPK
BATCP
ATR ligand 2
Cesium chloride 7647
The structure
AF40431 181125
Cytotoxic alkaloids from Houttuynia cordata PMID 11794526
(2R)
Due to interleukin
碳酸酐酶 9（CA9）基因
Cytotoxic activity of bromodomain inhibitor NVS
LILRB2/CD85d/ILT
Methylarginine targeting chimeras for lysosomal degradation of intracellular proteins PMID 39414979
An In Vitro Microneutralization Assay for Influenza Virus Serology PMID 35848945
Structure Elucidation of Verucopeptin, a HIF
3
Nrtn
PNB
Structure
基质金属肽酶 17（MMP17）基因
(S,R,S)
Dammarane
Sae1 Mouse Pre
Selenocyanates and diselenides a new class of potent antileishmanial agents PMID 21571403
Xanthosine administration does not affect the proportion of epithelial stem cells in bovine mammary tissue, but has a latent negative effect on cell proliferation PMID 24992045
Antifungal effects of fluconazole (UK 49858), a new triazole antifungal, in vitro PMID 3021710
Discovery of a Novel 1,4
Novel mandelic acid derivatives containing piperazinyls as potential candidate fungicides against Monilinia fructicola Design, synthesis and mechanism study PMID 39024805
KSHV and HPV modulate epithelial
Medicinal foodstuffs. XXVIII. Inhibitors of nitric oxide production and new sesquiterpenes, zedoarofuran, 4
Profile of aclidinium bromide in the treatment of chronic obstructive pulmonary disease PMID 22003291
Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC PMID 37563309
NOSTRIN Human Pre
Aclidinium bromide, a new, long
Nfe2
ANT
Loxl3
Cfp
G Protein β
Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice PMID 20576641
Cucurbitacins as Constituents of Wilbrandia ebracteata PMID 17235971
1
Plasma levels of heat shock protein 72 (HSP72) and beta
Effect of tiplaxtinin (PAI
Studying organelle physiology with fusion protein
Role of platelet activating factor in ischaemia
9
SGLT inhibitor
Human gastric cathepsin E. Predicted sequence, localization to chromosome 1, and sequence homology with other aspartic proteinases PMID 2674141
Pulsatilla saponin D the antitumor principle from Pulsatilla koreana PMID 15473660
[Moldavoside
HVEM/TNFRSF14 蛋白, Human (HEK293, mFc)
Deficiency of BCAT2
Tyrosinase inhibitory effects of 1,3
Structure
(
Clofarabine
肌酸激酶，M 型（CKM）基因
TSLP from RSV
E
De novo mutation screening in childhood
Lifr
The Root Extract of Rosa multiflora Ameliorates Nonalcoholic Steatohepatitis Development via Blockade of De Novo Lipogenesis and Inflammation PMID 38921022
Rubrofusarin triglucoside 245724
Anticancer agent 30 2907774
Identification of a nonpeptide ligand that releases bioactive insulin
Mitochondrial ROS
Timiperone 57648
热休克蛋白家族 A (Hsp70) 成员 14（HSPA14）基因
Downregulation of acetyl
BTC1070
Tatsinine 90038
YM
肌动蛋白相关蛋白 2/3 复合物，亚基3（Arpc3）基因
New resorcylic acid derivatives of Lysimachia tengyuehensis against MRSA and VRE by interfering with bacterial metabolic imbalance PMID 39096819
CAM833 2758364
Aloe
甲基转移酶 9（METTL9）基因
Naxitamab 1879925
Ruboxistaurin hydrochloride (Standard)
Cecropin A (1
DHX9
KT
SLC6A14 Human Pre
Harnessing free energy calculations for kinome
PROTAC BRD4 Degrader
Rac/Cdc42 鸟嘌呤核苷酸交换因子 6（ARHGEF6）基因
Bioactive Phytochemicals from Mulberry Potential Anti
Elbasvir 1370468
Stopped
4
Combination of indoline with alepterolic acid produces potent anti
Marine Fungi from the Sponge Grantia compressa Biodiversity, Chemodiversity, and Biotechnological Potential PMID 30978942
Peripheral nervous system lymphatic vessels A simple delivery route to promote nerve regeneration PMID 38688418
Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia
Azidoethyl
BuChE
Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM
3,4
Influenza C virus susceptibility to antivirals with different mechanisms of action PMID 38587392
Methyllysine binding domains Structural insight and small molecule probe development PMID 28478342
dna
Anticancer effects of bufalin on human hepatocellular carcinoma HepG2 cells roles of apoptosis and autophagy PMID 23344047
(2S,3R)
Isodihydroauroglaucin 74886
Ivermectin, a new candidate therapeutic against SARS
Spns2
RS 09 1449566
eIF3a sustains non
KYA1797K 1956356
Antioxidative natural product protect against econazole
VRK1/CK1
Inhibition of follicle
A root
Nutraceutical and therapeutic potential of Phycocyanobilin for treating Alzheimer's disease PMID 34047285
SORT
BMS
hsa
Diphtheria toxin CRM197
CLOCK 交互起搏器（CIPC）基因
同源框 D8（HOXD8）基因
Tumor burden limits bispecific antibody efficacy through T cell exhaustion averted by concurrent cytotoxic therapy PMID 34258584
Heterophyllin A 145459
Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders PMID 27096048
LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation PMID 9435190
Microcystin
ALK5
Neplanocin A. A potent inhibitor of S
Naringenin
Alkyne cyanine dye 718 1188292
A novel mechanism regulating pyroptosis
Koreanoside G 2348441
The tumor
Technical Support
Ganoderic acid N 110241
TP
PRDX1 promotes testosterone synthesis and attenuates aging via redox regulation of ATG4B to modulate lipophagy PMID 41261096
m
含 Src 同源 2 结构域的转化蛋白 D（SHD）基因
Pilabactam 2410688
Evaluation of the hydrating benefits of a cationic hyaluronic acid From biological evaluation to consumer home use trial PMID 38685748
Antifungal agent125
Experimental study of the anti
Ethacizine 33414
Sodium Dodecyl Sulfate
A brief overview on recent advances in spiro[chromane
Simtuzumab 1318075
Reduction of TRPC1/TRPC3 mediated Ca2+
Demethylzeylasteral inhibits osteosarcoma cell proliferation by regulating METTL17
Aspartame a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies PMID 17828671
ONO
Discovery of pan
Design and synthesis of pironetin analogue/combretastatin A
Naturally occurring glycan forms of human immunoglobulins G1 and G2 PMID 20444501
2,5
2,5
Glycochenodeoxycholic acid 3
Genetic insights into the in vivo functions of prostaglandin signaling PMID 23685076
A novel MyD88 inhibitor LM9 prevents atherosclerosis by regulating inflammatory responses and oxidative stress in macrophages PMID 30880215
Galanthamine from snowdrop
Humanizing murine IgG3 anti
Chlorothalonil induces the intestinal epithelial barrier dysfunction in Caco
α
Stachyose tetrahydrate 10094
Firefly luciferase
TNFAIP6 Human Pre
Antioxidant phenolic compounds from the rhizomes of Astilbe rivularis PMID 28361551
Metformin inhibits the proliferation of rheumatoid arthritis fibroblast
PROTAC EED degrader
The interaction of a β2 adrenoceptor agonist drug with biomimetic cell membrane models The case of terbutaline sulphate PMID 34592235
SAR and species/stereo
Peroxygenase activity of cytochrome c peroxidase and three apolar distal heme pocket mutants hydroxylation of 1
In vitro selection of a peptide with high selectivity for cardiomyocytes in vivo PMID 15313615
CB17.SCID mice
TG 100713 925705
MCE
Purinostat 1929583
Tryptamine
Caffeic acid oligomers in Lithospermum erythrorhizon cell suspension cultures PMID 10746877
DYB
Bioresorbable, electrospun nonwoven for delayed and prolonged release of temozolomide and nimorazole PMID 33567313
Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism PMID 10574966
IFNAR1
Lgals9 Rat Pre
A new G
Ferroptosis promotes sepsis
MCE
SCP
15
Expression of HER2 in high
Deep analysis of acquired resistance to FGFR1 inhibitor identifies MET and AKT activation and an expansion of AKT1 mutant cells PMID 30140389
5
m6A reader IGF2BP1 facilitates macrophage glycolytic metabolism and fibrotic phenotype by stabilizing THBS1 mRNA to promote pulmonary fibrosis PMID 40220148
gamma
Design, synthesis and biological evaluation of dual Bcl
Otaplimastat 1176758
The Effect of Antitumor Antibiotic Olivomycin A and Its New Semi
Discovery of Novel 2,3
Novel class of benzoic acid ester derivatives as potent PDE4 inhibitors for inhaled administration in the treatment of respiratory diseases PMID 24400806
PPM1G 抗体 (YA1698)（PPM1G Antibody (YA1698)）
Texas Red (Standard) (磺基罗丹明 101 (标准品))
Toward the rational design of protein kinase casein kinase
Demethylzeylasteral ameliorates inflammation in a rat model of unilateral ureteral obstruction through inhibiting activation of the NF‑κB pathway PMID 28534978
(
Silicon Incorporated Morpholine Antifungals Design, Synthesis, and Biological Evaluation PMID 26617963
MCE
(
Cadherin
Two fold modified chitosan for enhanced adsorption of hexavalent chromium from simulated wastewater and industrial effluents PMID 27112874
Development of anti
MCE
Genetic Incorporation of ε
Demethylzeylasteral inhibits proliferation and metastasis of osteosarcoma cells by modulating the PI3K/AKT/Autophagy pathways PMID 40655907
NSC781406 1676893
PRGL493 2479378
Knowledge and Structure
Anti
Naproxen
Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4
Saponin D 79190
Ccne1
A 74704 129467
Taglutimide (Biglumide)
T 82
Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α
rno
UK140
Nastorazepide hemicalcium 343326
WP 1122
TAPI
TGX
B3GALT5 Human Pre
RMC
In vitro expansion of the mammary stem/progenitor cell population by xanthosine treatment PMID 22698263
PGE1 abolishes the mitochondrial
Cetirizine
2
Tetramethylpyrazine improves the structure and function of mitochondrial
Lhx9 Rat Pre
AZD7325 942437
Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors PMID 28537878
SAH
MCT1
Aminoacyl
Fibrate
Deprotection of S
CD19
High
Il36a
降钙素相关多肽β（CALCB）基因
4,3' 6',2" 5",4'"
4
Design, synthesis and biological characterization of selective LIMK inhibitors PMID 26233434
DHX9
Tachykinins and their receptors contributions to physiological control and the mechanisms of disease PMID 24382888
Prostaglandin analogs as inhibitors of tumor cell DNA synthesis PMID 7220548
Nickelate(4
Adenosine and the adenosine A2A receptor agonist, CGS21680, upregulate CD39 and CD73 expression through E2F
2
TrimTAC1 3095569
Pharmacokinetics of Gentamicin Components C1, C1a, and C2/C2a/C2b and Subsequent Decline in Glomerular Filtration Rate in Neonates PMID 35760955
DL
Radulone A 221374
Conalbumin 1391
Effect of the small molecule plasminogen activator inhibitor
Processing and activation of pro
DA
MG53 inhibits ferroptosis by targeting the p53/SLC7A11/GPX4 pathway to alleviate doxorubicin
Sulfo
Paeciloquinones A, B, C, D, E and F new potent inhibitors of protein tyrosine kinases produced by Paecilomyces carneus. I. Taxonomy, fermentation, isolation and biological activity PMID 7730151
Hypoxia
N
Determination of the effect of calcineurin inhibitors on the rat's immune system after KLH immunisation PMID 15093258
MCE
Design, synthesis and evaluation of 2
Amino acid based prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents PMID 30692024
BMS
UNC6535 TFA
Propylene thiourea (4
XYD270
Raphanus sativus extract
MCE
B4galt3 Mouse Pre
AZD
Efna1
Examination of the xanthosine response on gene expression of mammary epithelial cells using RNA
单链 DNA 结合蛋白 1（SSBP1）基因
dimeric interface
Design and optimization of hybrid of 2,4
N
2
mRNA Delivery Using Bioreducible Lipidoid Nanoparticles Facilitates Neural Differentiation of Human Mesenchymal Stem Cells PMID 32815325
R1
Dihydrexidine
Hongjingtian Injection Inhibits Proliferation and Migration and Promotes Apoptosis in High Glucose
Glycyl
ITK degrader 2 2858738
MCE
Mcl
GC
B4galt1 Rat Pre
Intrapleural dual blockade of IL
19(S)
P
Fc
CD44 Participates to Extramedullary Haematopoiesis Onset by Mediating the Interplay Between Monocytes and Haematopoietic Stem Cells in Myelofibrosis PMID 40690545
B4GALT7 Human Pre
TACI 抗体 (YA3511)（TACI Antibody (YA3511)）
Thespesenone and dehydrooxoperezinone
Etanercept An overview PMID 12894133
Treatment of oral erosive lichen planus with 1% pimecrolimus cream a double
Euchrestaflavanone B 87402
Eif2ak1
m
Demethylzeylasteral inhibits cell proliferation and induces apoptosis through suppressing MCL1 in melanoma cells PMID 29072681
Med1
11
Design of selective, ATP
Fenvalerate
Three non
AP
Klf15
3
Ventromorphins A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway PMID 28787124
Vacuolar transport of abscisic acid glucosyl ester is mediated by ATP
6,6''
4
A single
Sitravatinib is a potential EGFR inhibitor and induce a new death phenotype in Glioblastoma PMID 37322389
Fujenal, a diterpenoid saga of neighbouring group participation PMID 18589462
Icam1
共997页
首页
上一页
934
933
932
931
930
929
928
927
926
925
924
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新