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WM
胆绿素还原酶 B（BLVRB）基因
Toward Environmentally Benign Electrophilic Chlorinations From Chloroperoxidase to Bioinspired Isoporphyrins PMID 35574587
W1131 2740522
Histochemical and biochemical studies of dipeptidyl peptidase I (DPP I) in laboratory rodents PMID 1801517
5
Discovery of NVP
Casodex preclinical studies and controversies PMID 7625752
SCYX
Trospium chloride in the management of overactive bladder PMID 15482001
α
Spermine Prodrug
Erythropoietin
Adrenoceptor activity of muscarinic toxins identified from mamba venoms PMID 21557730
WIN 62577 138091
Self
转化生长因子 β 1（TGFB1）基因
Protective Effects of the Wenfei Buqi Tongluo Formula on the Inflammation in Idiopathic Pulmonary Fibrosis through Inhibiting the TLR4/MyD88/NF
Peptide
4'
Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes PMID 9918925
An S100A8/A9 Neutralizing Antibody Potently Ameliorates Contact Hypersensitivity and Atopic Dermatitis Symptoms PMID 39848567
Anti
SMI
C2 Adamantanyl globotriaosylceramide (d18 1/2 0) 261155
The Dipeptidyl Peptidase
Cyclo(l
4
TKS 159
GK13R
KG
Discovery of novel dipeptidyl peptidase
ALN
CL15H6
SC
Nemadectin (90%) (CL
Preclinical evaluation of a radioiodinated fully human antibody for in vivo imaging of vascular adhesion protein
FIT
Farnesoid X receptor alpha ligands inhibit HDV in vitro replication and virion infectivity PMID 37058078
BMS
Synthesis of phenoxyacetic acid derivatives as highly potent antagonists of gastrin/cholecystokinin
Benzyl
SNHG20/miR
Analysis of supplements available to UK consumers purporting to contain selective androgen receptor modulators PMID 32748554
Treatment of head and neck cancer with CHART and nimorazole phase II study PMID 12559522
Mephenytoin
Mutagenic properties of oxidized GTP and ATP in in vitro transcription
PH
Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small
Citromycetins and bilains A
A review of the neuroprotective properties of the 5
Hydropersulfides Inhibit Lipid Peroxidation and Protect Cells from Ferroptosis PMID 35977425
Piketoprofen 60576
Albizziin 585
Exosomes derived from oral squamous cell carcinoma tissue accelerate diabetic wound healing PMID 37154491
Nrf2 and its dependent autophagy activation cooperatively counteract ferroptosis to alleviate acute liver injury PMID 36410674
Dactylocycline A
6
KSQ
F
Targeted Delivery of Functionalized Upconversion Nanoparticles for Externally Triggered Photothermal/Photodynamic Therapies of Brain Glioblastoma PMID 29507632
Sigma ligands, but not N
Flavanoids from Caesalpinia pulcherrima PMID 12877920
Ambulatory monitoring and exercise testing in the evaluation of a new long
SUGT1 Human Pre
磷酸二酯酶 4D（PDE4D）基因
Integrated innate mechanisms involved in airway allergic inflammation to the serine protease subtilisin PMID 25876764
IBI
chromatin binding
Discovery of dCDK9
RG 14921 144909
Staining of intracellular deposits of uranium in cultured murine macrophages PMID 11871745
Altered potassium ATP channel signaling in mesenteric arteries of old high salt
The dynamic changes of several reproductive hormones during termination of early pregnancy by RU486 in combination with PG
Isolation of tyrosinase inhibitors from Artocarpus heterophyllus and use of its extract as antibrowning agent PMID 18683821
The pharmacology of RS
Carboxyamidotriazole exerts anti
A small molecule activator of Nav 1.1 channels increases fast
KU
Fscn1 Mouse Pre
(rac)
Puerarin Alleviates Alcoholic Liver Disease via Suppressing Lipolysis Induced by Sympathetic Outflow PMID 40374377
PROTAC USP7 Degrader
BR 丝氨酸/苏氨酸激酶 1（BRSK1）基因
Estrogen receptor antagonist 2 2735803
Identification of autophagy
TROY interacts with RKIP to promote glioma development PMID 30337686
Peptidoglycan isolated from the fruit of Lycium barbarum alleviates liver fibrosis in mice by regulating the TGF
PI3K
Ultra
Dual intra
Celastrol Combats Methicillin
Prkcd Mouse Pre
PRKCD Human Pre
Sulisatin disodium 54935
GSK2801, a BAZ2/BRD9 Bromodomain Inhibitor, Synergizes with BET Inhibitors to Induce Apoptosis in Triple
GATA
Manganese acetate tetrahydrate 6156
Role of GSK
Clavulanate potassium 61177
Anticancer agent 209 545445
Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active
The costimulation
Isolation of oxidative degradation products of atorvastatin with supercritical fluid chromatography PMID 26010538
PDX regulates inflammatory cell infiltration via resident macrophage in LPS
9
Discovery of novel chiral diazepines as bombesin receptor subtype
Mucin overexpression limits the effectiveness of 5
Inhibition of Interleukin
The complement and contact activation systems partnership in pathogenesis beyond angioedema PMID 27782339
ECI830 3054692
(6E)
Rbpj
Delivery of Proteins, Peptides or Cell
Ac
Stimulation of Suicidal Erythrocyte Death by Tafenoquine PMID 27855400
Small
Bazedoxifene
Sanzi Yangqin Decoction alleviated epithelial barrier damage in acute lung injury by mediating CD40 in alveolar macrophages to inhibit necroptosis of pulmonary epithelial cells PMID 41344274
The DNA
EWP 815 20231
Multiple myeloma regression mediated by bruceantin PMID 14871997
Copine 1 predicts poor clinical outcomes by promoting M2 macrophage activation in ovarian cancer PMID 37747823
Inhibition of store
Synthesis of Tricyclic Pterolobirin H Analogue Evaluation of Anticancer and Anti
ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis PMID 32277030
RNA Interference Screen to Identify Kinases That Suppress Rescue of ΔF508
Gymnemic acid I triggers mechanistic target of rapamycin
3
ATC0065 free base 509145
Impaired adrenergic agonist
The origin and application of experimental autoimmune encephalomyelitis PMID 17917672
Exosomal lncRNA ATB Derived from Ovarian Cancer Cells Promotes Angiogenesis via Regulating miR
A brainstem
Tnfsf13b
[Prothrombin
Protective Role of α
Dimethyl adipate 627
Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad
Activity of T
Synthesis and cytotoxicity evaluation of glycosidic derivatives of lawsone against breast cancer cell lines PMID 31810778
Abarelix for injectable suspension first
Naphtho[2,1
Animal
TGF
Stevioside E 1309929
Screening of a drug repurposing library with a nematode motility assay identifies promising anthelmintic hits against Cooperia oncophora and other ruminant parasites PMID 30638515
ACES 7365
17α
Nicotinamide 1,N6
Inosine induces acute hyperuricaemia in rhesus monkey (Macaca mulatta) as a potential disease animal model PMID 33715593
Mucoprotective effects of Saikosaponin
Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons PMID 9129468
Acylation derivatization based LC
Sorbitan monododecanoate 1338
2
Procaterol but not dexamethasone protects 16HBE cells from H₂O₂
GC
ras 同系物家族成员 U（RHOU）基因
CD200 Blockade Modulates Tumor Immune Microenvironment but Fails to Show Efficacy in Inhibiting Tumor Growth in a Murine Model of Melanoma PMID 34692697
RNF19B Human Pre
Dnm2
CXCL16 蛋白, Rat (HEK293, Fc)
Case Report Hyper IgM Syndrome Identified by Whole Genome Sequencing in a Young Syrian Man Presenting With Atypical, Severe and Recurrent Mucosal Leishmaniasis PMID 33013931
Synergistic Antibacterial Strategy of AIEgens Photosensitizer CPTQ for Photodynamic Therapy and Ferroptosis
TUBB3 Human Pre
The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models PMID 23736298
Exemestane metabolites Synthesis, stereochemical elucidation, biochemical activity and anti
Preclinical studies of opioids and opioid antagonists on gastrointestinal function PMID 15357851
Antiviral Activity of Hederasaponin B from Hedera helix against Enterovirus 71 Subgenotypes C3 and C4a PMID 24596620
New bioactive cyclopeptide alkaloids with rare terminal unit from the root bark of Ziziphus cambodiana PMID 35541146
In vitro and in vivo studies of the non
FN
CXCL6 Human Pre
BH3 profiling and a toolkit of BH3
Pno1 Rat Pre
A Novel Inhibitor of Homeodomain Interacting Protein Kinase 2 Mitigates Kidney Fibrosis through Inhibition of the TGF
KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules PMID 40157365
Kalopanax saponin G 171370
Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding PMID 30275017
SDH
Anti
Small molecule obatoclax (GX15
吲哚胺 2,3
Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation PMID 37847303
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism PMID 30131496
Effects of carboxyamidotriazole on in vitro models of imatinib
Etanercept in the treatment of rheumatoid arthritis PMID 18360618
PHGR1 Human Pre
Polychlorinated Dibenzo
Proline
Extraction of glyceric and glycolic acids from urine with tetrahydrofuran utility in detection of primary hyperoxaluria PMID 9267307
1,2
7ß,27
PROTAC EGFR degrader 9 2992670
11
Angiotensin converting enzyme
Thiosildenafil
(E)
富脯氨酸 16（PRR16）基因
Amdakefalin 2253747
Synthesis and characterization of NESS 0327 a novel putative antagonist of the CB1 cannabinoid receptor PMID 12663689
Mitochondrial targeted modification and anticancer mechanism of natural product ergosterol peroxide PMID 39106712
Anti
Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapy
CD44
Discovery and Structure
Efficient chemical conversion of louisianin A to C and D, the inhibitor of angiogenesis PMID 9127203
A genome
CFI
SGN
SFRP2 蛋白, Human (HEK293, His, solution)
Marsdenoside B 858360
Human apolipoprotein A
Design, Synthesis, and Study of the Insecticidal Activity of Novel Steroidal 1,3,4
Creg1
5
XY028
Calyciphylline A 596799
Temoporfin (Foscan®, 5,10,15,20
rel
MCE
Parvoline 1123
Rivaroxaban impurity 9 88777
Minnelide 1254702
Expanding the knowledge around antitubercular 5
Pyridafol (达草止)
Functional agonism of insect odorant receptor ion channels PMID 21555561
The Role of the Histone Methyltransferase EZH2 in Liver Inflammation and Fibrosis in STAM NASH Mice PMID 32370249
The central nervous system effects of the partial GABA
4
Python
Discovery of Next
Development of a cell
NPS2390, a Selective Calcium
Discovery of positive allosteric modulators and silent allosteric modulators of the μ
TNF
GeA
Musk
Sodium Hyaluronate Hydroxypropyltrimonium Chloride 1714127
Novel 2
YM
MRX
The potential role of valsartan + AHU377 ( LCZ696 ) in the treatment of heart failure PMID 23663006
JAK2/STAT3
Kadsurenin A 145701
LAPC4
Cholecystokinin
MCE
MCE
TAO 激酶 2（TAOK2）基因
U50488 inhibits HIV
The Mac1 ADP
PI3K p85α/HIF
A small
Endothelial Gasdermin D Induces Mitochondrial Damage and Activates the STING Pathway in Lipopolysaccharide
Mechanistic Insights into Vorinostat as a Repositioned Modulator of TACE
A PTK7
16 0 Cardiolipin disodium (Diphosphatidylglycerol (16 0) disodium)
Recent advances of antibody drug conjugates for clinical applications PMID 33088681
α
2
NMDAR blocker 1
ETA antagonist 2
4
4
N
New inhibitor targeting Acyl
Gilteritinib
PSMA
神经母细胞瘤ras癌基因（Nras）基因
Pyruvic acid
113
Glutamate transporter SLC1A6 promotes resistance to immunotherapy in cancer PMID 40481876
A highly selective inhibitor of interleukin
Protoilludane sesquiterpenes from the wood decomposing fungus Granulobasidium vellereum (Ellis & Cragin) Jülich PMID 23517685
Anti
Effect of cytochrome P
Scaffolding
neurexophilin 和 PC 酯酶域家族成员 3（NXPE3）基因
基质金属肽酶 3（MMP3）基因
[2,2' 6',2''
Linomide (roquinimex) affects the balance between pro
food safety
alpha
Copper tripeptide 89030
Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis PMID 38141410
1
Amphiphilic conjugates of human brain natriuretic peptide designed for oral delivery in vitro activity screening PMID 16536455
MCE
Design and synthesis of conformationally restricted capsaicin analogues based in the 1, 3, 4
Scap
Desmethyl Naproxen
Hepatic micropeptide modulates mitochondrial RNA processing machinery in hepatocellular carcinoma PMID 40513568
Beta Receptor
Serine protease inhibitors modulate smoke
MEK
RXR antagonist 5 1807740
R
Neuronal substance P
nAChR agonist 1 1394371
Expression of the activin axis and neuronal rescue effects of recombinant activin A following hypoxic
4
Architectural transcription factors collectively shape nuclear radial positioning of chromatin contacts PMID 40880471
2,2',2'',2'''
Combination therapy with artemether and enalapril improves type 1 diabetic nephropathy through enhancing antioxidant defense PMID 35173839
丝氨酸棕榈酰转移酶长链碱基亚基 1（SPTLC1）基因
Discovery of Tetralones as Potent and Selective Inhibitors of Acyl
(3S,4R,5S)
PLGLAG
Effects of mesulergine treatment on diet selection, brain serotonin (5
MCE
Potentiating α2 subunit containing perisomatic GABAA receptors protects against seizures in a mouse model of Dravet syndrome PMID 31045243
TAPI
FA 核心复合物相关蛋白 100（FAAP100）基因
Glycocalyx
3'
The rise and fall of the CD28 superagonist TGN1412 and its return as TAB08 a personal account PMID 27191544
(S)
Structure
[1,1' 3',1'' 4'',1'''
DHX9
Titanium oxide phthalocyanine
Fragment
The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA PMID 12957370
3’
gamma
3
1,3
TNF
Antiarol rutinoside 261351
Isoquinoline 119
Seven new sesquiterpene glycosides from the root bark of Dictamnus dasycarpus PMID 11473427
Inhibition of MCF
A microbiological assay to estimate the antimicrobial activity of parenteral tildipirosin against foodborne pathogens and commensals in the colon of beef cattle and pigs PMID 26538405
Tnfrsf4
A novel semi
A new proteasome inhibitor, TP
Cutting
The photodynamic activities of dimethyl 131
Synthesis, SAR and pharmacology of CP
Fmoc
Introduction Click Chemistry PMID 34157843
β1
Br
Methyl Paraben Affects Porcine Oocyte Maturation Through Mitochondrial Dysfunction PMID 39595642
NAD deficiency contributes to progressive kidney disease in HIV nephropathy mice PMID 38961841
Testing the polar auxin transport model with a selective plasma membrane H+
MCE
TKP
DU172
LCP
Upregulation of glutamate transporter 1 by mTOR/Akt pathway in astrocyte culture during oxygen
Evaluation of anxiolytic effects of aripiprazole and hydroxyzine as a combination in mice PMID 27999468
DOBAQ 1360461
Targeted protein degradation mechanisms, strategies and application PMID 35379777
MSC
MLANA
Adipose triglyceride lipase activity is inhibited by long
MCE
Glycogen synthase kinase
Trilobatin 2''
SKF 83959 hydrobromide 67287
MCE
4,7
S100A7 orchestrates neutrophil chemotaxis and drives neutrophil extracellular traps (NETs) formation to facilitate lymph node metastasis in cervical cancer patients PMID 39384116
Epigenetic activation of secretory phenotypes in senescence by the FOXQ1
Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production PMID 12496265
Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow PMID 11179434
Glycolytic reprogramming shapes the histone acetylation profile of activated CD4+ T cells in juvenile idiopathic arthritis PMID 40009514
BODIPY TMR Lyso PC ester 2260795
HDAC I/IIb selective inhibitor Purinostat Mesylate combined with GLS1 inhibition effectively eliminates CML stem cells PMID 36185739
Natural Product BO
L
SMIM3 Human Pre
Anti
A Disintegrin and Metalloproteinase Domain 17 Regulates Colorectal Cancer Stem Cells and Chemosensitivity Via Notch1 Signaling PMID 26744411
Small
Discovery of MK
Bufalin induces apoptosis in vitro and has Antitumor activity against human lung cancer xenografts in vivo PMID 27444971
PSCA 蛋白, Mouse (HEK293, Fc)
Phellodendrine ameliorates intestinal inflammation and protects mucosal barrier via modulating COL1A1, VCAM1 and IL
Sequential SDF
Delphinidin 3
Platelet
Small molecule antagonists of Tcf4/beta
Basic N
Isosteric replacements of the carboxylic acid of drug candidate VX
Soluble E
COTI
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety PMID 27639989
TUG
Structure
Sugar
Gga3 Mouse Pre
Activation of mineralocorticoid receptor by ecdysone, an adaptogenic and anabolic ecdysteroid, promotes glomerular injury and proteinuria involving overactive GSK3β pathway signaling PMID 30111886
Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14 PMID 37995679
Purification of antibodies and antibody fragments using CaptureSelect™ affinity resins PMID 24515474
Targeting human SET1/MLL family of proteins PMID 28160335
Disodium succinate
β
Gfra1 Rat Pre
Pharmacokinetic parameters of three active ingredients hederacoside C, hederacoside D, and ɑ
2 E,4 E
P
The voltage
GALA
TPT3TP
dTPT3TP
AH23848
AGN192093
REGN3124
AGH
TT
Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation PMID 41771535
Induction of CYP2B6 and CYP3A4 expression by 1
Cyanobufalins Cardioactive Toxins from Cyanobacterial Blooms PMID 30369239
Primidone blocks RIPK1
Saikosaponin A inhibits IL
CXC 基序趋化因子配体 5（CXCL5）基因
NNC 55
Astins A and B, antitumor cyclic pentapeptides from Aster tataricus PMID 8339347
VU6005806/AZN
Sarcosine Dehydrogenase, Pseudomonas sp.
1,3,5
Lyciumin D
Benzofuran
N
Determination of Gymnemic Acid I as a Protein Biosynthesis Inhibitor Using Chemical Proteomics PMID 28256837
Fibronectin 蛋白, Human (314a.a, HEK293, His)
XRCC4 Human Pre
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells PMID 29547833
Beneficial Effects of Celastrol on Immune Balance by Modulating Gut Microbiota in Experimental Ulcerative Colitis Mice PMID 35609771
Constitutively active ESR1 mutations in gynecologic malignancies and clinical response to estrogen
2′
NLR 家族成员 X1（Nlrx1）基因
Origin of the kinetic HDAC2
孕激素受体（Pgr）基因
Structural modification of Fas C
(
Norepinephrine
G
Identification of a novel PDE4 inhibitor inspired by leoligin
Plantaricin A, a peptide pheromone produced by Lactobacillus plantarum, permeabilizes the cell membrane of both normal and cancerous lymphocytes and neuronal cells PMID 20416350
Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol
Bcl
Hemoglobin subunit theta
C.I. Direct Violet 9 6227
Doxefazepam (Standard) (SAS
Conserved Herpesvirus Kinase ORF36 Activates B2 Retrotransposons during Murine Gammaherpesvirus Infection PMID 32404524
Anti
PKM2
Tafenoquine and NPC
JNJ872 inhibits influenza A virus replication without altering cellular antiviral responses PMID 27451344
Leukotriene F4 83851
EP3 antagonist 3 1227827
VCP downstream metabolite glycerol
The research progress of SARS
Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation PMID 30815844
Mnat1 Rat Pre
TNFSF4
Nitroimidazoles as hypoxic cell radiosensitizers and hypoxia probes misonidazole, myths and mistakes PMID 29303355
Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant
Fmoc
Discovery of SET domain
Recent Progress in Bioconjugation Strategies for Liposome
Clavulanic acid a beta
2,3',4,4',5,5'
N
MCE
Claramine 1430194
WNT Activates the AAK1 Kinase to Promote Clathrin
Design and profiling of GS
Design, synthesis and pharmacological characterization of analogs of 2
CYM
Bcl
The discovery of pyridalyl a novel insecticidal agent for controlling lepidopterous pests PMID 14727738
5,5'
Synthesis and biological evaluation of CX
Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)
含卷曲螺旋结构域 152（CCDC152）基因
Oligodendrocyte progenitor cells are paired with GABA neurons in the mouse dorsal cortex Unbiased stereological analysis PMID 28827179
Deltamethrin induced RIPK3
Pharmacokinetic and Metabolism Studies of Monomethyl Auristatin F via Liquid Chromatography
reactive activity
Expression and biochemical characterization of the human enzyme N
Toxicity of the veterinary sulfonamide antibiotic sulfamonomethoxine to five aquatic organisms PMID 25461547
Functional induction of P
Structure Elucidation, Conformation, and Configuration of Cytotoxic 6
2
Wdr18
Characterization of CADD522, a small molecule that inhibits RUNX2
Exosomes secreted from induced pluripotent stem cell ameliorate the lipopolysaccharide induced neuroinflammatory response via lncRNA
UNC0321 1238673
Co
L
谷氨酸离子型受体红藻氨酸亚基 5（GRIK5）基因
Interaction between platelet receptor and iloprost isomers PMID 2456096
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